Simultaneous involvement of Brain and Peripheral nerves in a Child with Systemic Lupus Erythematosus (SLE): A Case Report.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that affects almost every system in the body. Neuropsychiatric symptoms are common in SLE, but diagnosis often remains difficult. In this case, we report a girl of 16 years who presented with an acute confusional state and features of peripheral neuropathy. A detailed clinical evaluation with a review of the medical history and appropriate laboratory analyses allows this diagnosis to be made. Treatment with immune-modulating therapy, cyclophosphamide resulted in significant improvement of her symptoms. Neuropsychiatric SLE should be considered a potential differential diagnosis for patients presenting with acute confusional state and peripheral neuropathy. [ABSTRACT FROM AUTHOR]