A relationship study between different parameters and standardized uptake values of normal liver by using positron emission tomography / computed tomography scan.

المقال يركز على العلاقة بين معايير مختلفة وقيم الامتصاص القياسية (SUVmax) لأنسجة الكبد الطبيعية كما تم تقييمها بواسطة فحوصات التصوير المقطعي بالإصدار البوزيتروني/التصوير المقطعي المحوسب (PET/CT). شملت الدراسة 100 مشارك ووجدت ارتباطًا ذا دلالة إحصائية بين SUVmax ومؤشر كتلة الجسم (BMI)، مما يشير إلى أن امتصاص الكبد للعلامة المشعة 18F-FDG يزداد مع ارتفاع مؤشر كتلة الجسم. بالإضافة إلى ذلك، أظهرت النتائج أن المرضى الذكور أظهروا قيم SUVmax أعلى مقارنة بالإناث، حيث تم تحديد كل من الجنس ومؤشر كتلة الجسم كمتنبئين موثوقين لقيم SUV. تشير النتائج إلى أن فهم هذه العلاقات أمر حاسم لتفسير فحوصات PET/CT بدقة في البيئات السريرية. [Extracted from the article]

Background: Integrated Positron Emission Tomography (PET) is widely used to diagnose, stage, and track human diseases during whole-body scanning. Standardized uptake values (SUVmax) of normal organs were evaluated by Fluorlne-18-Fluoro-2-doxyD-glucose [18F-FDG (PET/CT)] scanning. Multimodality imaging is an interesting area of research that aims to study the relationship between SUVmax in normal livers and different parameters determined with PET/CT. Materials and Methods: A total of 100 people were tested for 18F-FDG PET/CT. All participants fasted for at least 6 hours before PET/CT imaging, and their fasting blood glucose levels were normal. Scans were acquired following an intravenous dose of 18F-FDG, and PET scans were collected 45-90 minutes after FDG injection. We measured the SUVmax in the livers of persons with normal BMI, high BMI, and obesity. Results: After adjusting each SUVmax based on the results of the BMI calculation, which were determined for each subject based on their height and weight, the relationship between SUVmax and BMI was statistically significant (p value < 0.05). The SUV measurement was greater in males than females, and it increased significantly in both male and female overweight and obese patients. Gender and BMI were the most reliable independent predictors of SUV value. Conclusion: The hepatic absorption of 18FFDG increases with the patient's BMI. Patients' genders are the independent variables that best predict their hepatic SUV values. [ABSTRACT FROM AUTHOR]

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