Isolation and Identification of Individual Intestinal Bacteria Associated with Waist Circumference Increase.

المقال يركز على العلاقة بين البكتيريا المعوية وزيادة محيط الخصر بين المشاركين، خاصة في سياق السمنة والسكري. قامت الدراسة بتحليل 180 عينة من إناث تتراوح أعمارهن بين 20 إلى 60 عامًا، وكشفت عن اختلافات كبيرة في الفلورا المعوية لدى المشاركات البدينات مقارنةً بأولئك ذوات الوزن الطبيعي، مع انتشار أعلى للبكتيريا سالبة الجرام في المجموعة البدينة. تشير النتائج إلى أن بكتيريا معوية معينة قد تلعب دورًا في تطور السمنة والسكري من النوع الثاني، مما يشير إلى إمكانيات جديدة لاستراتيجيات الوقاية من السمنة. كما تسلط الدراسة الضوء على العلاقة بين مؤشر كتلة الجسم، ومحيط الخصر، ومستويات فيتامين د3 بين المشاركين. [Extracted from the article]

Background: The bacterial flora of the gastrointestinal tract (GIT) of humans, there are differences in the composition of the flora which are influenced by age, diet, cultural conditions, and the use of antibiotics. Since the origin of obesity is multifactorial and complex, resulting from the interaction between genetic/epigenetic, environmental, and socio-psychological determinants, in addition to the bacterial composition of the intestinal flora could be a third element involved in the development of excess weight. Therefore intestinal flora plays an intermediary role in the metabolism and inflammation and is involved in the pathogenesis of diabetes type 2 and obesity. Objectives: This study aimed to draw the relationship between identified intestinal bacterial types on increasing the waist circumference among study participants. Materials and Methods: This study included the collection of 180 samples from participants (20–60 years) during the period from December 2022 to June 2023. Body mass index and waist circumference were calculated for study participants and intestinal bacteria was microbiologically and biochemically identified. Results: Results obtained showed that the intestinal flora of obese participants is significantly (P < 0.001) different from that of thin and normal participants. This flora was characterized by the presence of high levels of Gram's negative at the percentage (80.6% in obese), and Gram's positive at the percentage (19.4% in obese), with higher body mass index and waist circumference than those participants, with lower body mass index and waist circumference. Conclusion: This study showed a significant relationship between intestinal bacteria and diabetic patients with increased body mass index and waist circumference, leading to probable useful tools for developing strategies to prevent obesity. [ABSTRACT FROM AUTHOR]

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