Latest research progress in application of single-cell transcriptome sequencing technology in autoimmune diseases.

Single-cell RNA sequencing technology takes a single cell as research object, counts and analyzes the gene expression level of each transcript and heterogeneity between cells. This technology makes up for the defects of traditional sequencing technology to some extent. Autoimmune disease is the damage or dysfunction of autotissue cells caused by autoimmune tolerance or abnormal regulation of autoimmunity cells. In this paper, the research results on application of single-cell RNA sequencing technology in autoimmune disease in recent years are reviewed, which provides valuable clues for early realization of precise medical treatment. [ABSTRACT FROM AUTHOR]