The Base Hit: Neurological Diseases and Genetic Susceptibilities to Pesticide Exposures.

The article discusses a study published in the issue which explored a computational approach to connect pesticide exposures with generic variants associated with Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS). Topics include importance of understanding genetic susceptibility to pesticides, the reliance of traditional methods of assessing gene-environment interactions on large longitudinal studies, and strength of the study.