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Antibacterial Activity of Some Iranian Herbal Essential Oils as Disinfectant Agents on Surfaces Contaminated with Methicillin-resistant-Staphylococcus Aureus and Carbapenem-resistant-Pseudomonas Aeruginosa.

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  • معلومة اضافية
    • نبذة مختصرة :
      Background & Objectives: Different essential oils (EOs) with antibacterial activities are promising natural sources for providing novel disinfectant agents for hospital surfaces. Materials & Methods: The component and antibacterial effects of six EOs, including Cuminum cyminum (CCEO), Artemisia sieberi (ASEO), Laurus nobilis (LNEO), Ferula gummosa (FGEO), Lippia citriodora (LCEO), and Cymbopogon citratus (CIEO) were assessed by GC-MS and 96-well micro-plates (IC50), against Staphylococcus aureus (S. aureus) ATCC 25923, Pseudomonas aeruginosa (P. aeruginosa) ATCC 27853 and clinical isolates of methicillin -resistant S. aureus (MRSA) and metallo-beta-lactamase (MBL)-producing P. aeruginosa. Then, the antibacterial effects of FGEO, the most effective EO, were evaluated on the trolley surface in a hospital for 1, 3, 5 and 10 min intervals. Results: CCEO, ASEO, and FGEO exerted the highest antibacterial activity against S. aureus, while CIEO and LNEO inferred the highest activity against P. aeruginosa. In addition, FGEO mitigated the growth of S. aureus and P. aeruginosa on the trolley surface (P<0.05). Conclusion: The studied EOs could be novel encouraging agents to develop further green antimicrobial agents against different infections. In addition, FGEO exhibited considerable antibacterial effects on the surface of the trolley. [ABSTRACT FROM AUTHOR]
    • نبذة مختصرة :
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