Lesionectomy for Temporal Lobe Lesion can Result in Reduced Need of Antiepileptic Drugs.

BACKGROUND: Seizure outcomes after lesionectomy have been proven to be equivalent to excision, which ablates the epileptogenic cortex with the lesion. Different forms of resection surgery, as well as temporal lobectomy, are being investigated as therapeutic options for people with focal epilepsy who have not responded to medication. Although seizure control is the primary goal of epilepsy surgery, lowering or quitting antiepileptic drugs (AEDs) following epilepsy surgery is also an essential goal for patients and epileptologists. CASE PRESENTATION: We described a thirteen-year-old female who had suffered from headaches and multiple bouts of complex partial seizures for three years before undergoing surgery for a well-circumscribed lesion occupying the medial portion of the left temporal lobe next to the pole, with modest compression of the ipsilateral crus of the midbrain. Following surgery, the patient was kept on levetiracetam and phenytoin, which was later converted to a single antiepileptic drug with complete seizure control. CONCLUSION: Patients on multiple antiepileptic drugs for control of temporal lobe lesional seizures can be kept on a single antiepileptic drug after resection of the lesion and slowly the dose can be reduced. [ABSTRACT FROM AUTHOR]

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