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The effect of BIS-guided anaesthesia on the incidence of postoperative nausea and vomiting in children: a prospective randomized double-blind study.
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- المؤلفون: Frelich, Michal1,2; Sklienka, Peter1,2; Romanová, Tereza1; Němcová, Simona1; Bílená, Markéta1; Straková, Hana1; Lečbychová, Karolína1; Jor, Ondřej1,2; Formánek, Martin2,3; Burša, Filip1,2
- المصدر:
BMC Anesthesiology. 7/9/2024, Vol. 24 Issue 1, p1-7. 7p.
- الموضوع:
- معلومة اضافية
- الموضوع:
- نبذة مختصرة :
Background: Postoperative nausea and vomiting (PONV) is a significant problem following paediatric surgery, and volatile anaesthetics are an important cause of this phenomenon. BIS-guided anaesthesia, by reducing the consumption of anaesthetics, leads to a decrease in PONV in adult patients. Study objective: Evaluate the role of BIS-guided anaesthesia in reducing the incidence of paediatric PONV. Design: Prospective, randomized, double-blind study. Setting: A single center study in university hospital in Czech republic, from June 2021 to November 2022. Patients: A total of 163 children, aged 3–8 years with ASA I-II who underwent endoscopic adenoidectomy under general anaesthesia were included. Interventions: In the intervention group, the depth of anaesthesia was maintained to values between 40 and 60 of BIS. Main outcome measure: The primary outcome was the incidence of postoperative nausea and vomiting during 24 h after surgery. Results: The use of BIS-guided anaesthesia led to a significant decrease in the incidence of nausea and vomiting compared to the control group [17% vs. 53%; RR (95%CI) 0.48 (0.27–0.86); p < 0.001and 16% vs. 34%; RR (95%CI) 0.33 (0.20–0.54); p = 0.01, respectively]. Conclusions: BIS-guided anaesthesia decreases the incidence of postoperative nausea and vomiting in children undergoing adenoidectomy. Trial registration: Clinicaltrials.gov identifier: NCT04466579. [ABSTRACT FROM AUTHOR]
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