Frontrunners in CNS Drug Delivery: Novel delivery technologies enhance brain penetration to target neurodegenerative diseases and glioblastomas.

DRUG therapy for Parkinson's disease; GENE therapy; PHARMACEUTICAL technology; GLIOMAS; ALZHEIMER'S disease; DIFFUSION of innovations; BLOOD-brain barrier; CENTRAL nervous system; DRUG delivery systems; NEURODEGENERATION; UNITED States. Food & Drug Administration; MONOCLONAL antibodies; DRUG approval; PHARMACY information services; DRUG development

The article highlights advancements in CNS (central nervous system) drug delivery, particularly focusing on overcoming the challenges posed by the blood-brain barrier (BBB) through innovative technologies such as neurotropic viruses, receptor-mediated transcytosis, and peptide shuttles. It discusses the potential of these approaches in facilitating the delivery of therapeutics for neurodegenerative diseases and glioblastomas.