Item request has been placed!
×
Item request cannot be made.
×
Processing Request
Piscichuvirus-Associated Severe Meningoencephalomyelitis in Aquatic Turtles, United States, 2009-2021.
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
- المؤلفون: Laovechprasit, Weerapong1; Young, Kelsey T.1; Stacy, Brian A.2; Tillis, Steven B.3; Ossiboff, Robert J.3; Vann, Jordan A.3; Subramaniam, Kuttichantran3; Agnew, Dalen W.4; Howerth, Elizabeth W.1; Jian Zhang1; Whitaker, Shayna5; Walker, Alicia5; Orgill, Andrew M.5; Howell, Lyndsey N.2; Shaver, Donna J.6; Donnelly, Kyle7; Foley, Allen M.8; Stanton, James B.1
- المصدر:
Emerging Infectious Diseases. Feb2024, Vol. 30 Issue 2, p280-288. 9p.
- الموضوع:
- معلومة اضافية
- الموضوع:
- نبذة مختصرة :
Viruses from a new species of piscichuvirus were strongly associated with severe lymphocytic meningoencephalomyelitis in several free-ranging aquatic turtles from 3 coastal US states during 2009-2021. Sequencing identified 2 variants (freshwater turtle neural virus 1 [FTuNV1] and sea turtle neural virus 1 [STuNV1]) of the new piscichuvirus species in 3 turtles of 3 species. In situ hybridization localized viral mRNA to the inflamed region of the central nervous system in all 3 sequenced isolates and in 2 of 3 additional nonsequenced isolates. All 3 sequenced isolates phylogenetically clustered with other vertebrate chuvirids within the genus Piscichuvirus. FTuNV1 and STuNV1 shared ≈92% pairwise amino acid identity of the large protein, which narrowly places them within the same novel species. The in situ association of the piscichuviruses in 5 of 6 turtles (representing 3 genera) with lymphocytic meningoencephalomyelitis suggests that piscichuviruses are a likely cause of lymphocytic meningoencephalomyelitis in freshwater and marine turtles. [ABSTRACT FROM AUTHOR]
No Comments.