Host factors exploited by retroviruses.

Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101190261 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-1534 (Electronic) Linking ISSN: 17401526 NLM ISO Abbreviation: Nat Rev Microbiol Subsets: MEDLINE

Original Publication: London, UK : Nature Pub. Group, c2003-

Virus Replication*; Cells/*virology ; Proteins/*physiology ; Retroviridae/*physiology; Animals ; Cell Nucleus/virology ; Humans ; Protein Biosynthesis ; Proteins/genetics ; Proviruses/physiology ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Retroviridae/genetics ; Retroviridae Proteins/biosynthesis ; Retroviridae Proteins/genetics ; Retroviridae Proteins/metabolism ; Transcription, Genetic ; Virus Integration ; Virus Internalization

Retroviruses make a long and complex journey from outside the cell to the nucleus in the early stages of infection, and then an equally long journey back out again in the late stages of infection. Ongoing efforts are identifying an enormous array of cellular proteins that are used by the viruses in the course of their travels. These host factors are potential new targets for therapeutic intervention.

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0 (Proteins)
0 (RNA, Viral)
0 (Retroviridae Proteins)

Date Created: 20070228 Date Completed: 20070402 Latest Revision: 20240104

20250114

10.1038/nrmicro1541

17325726