نبذة مختصرة : Objective To analyze the epidemic characteristics of common pathogens in hospitalized children with acute respiratory infection in a medical institution in Shangrao from 2019 to 2021, so as to provide reference for the prevention and treatment of acute respiratory infection in children. Methods The serum samples of 920 children with acute respiratory tract infection in Shangrao Maternal and Child Health Hospital from 2019 to 2021 were collected, and the serum IgM antibodies were detected by indirect immunofluorescence to detect the common pathogens of acute respiratory tract infection. Statistical analysis was performed. Results The total detection rate of pathogens in acute respiratory tract infection was 38.91% (358/920). The detection rates of respiratory pathogens from 2019 to 2021 were 28.26% (91/322), 39.53% (119/301), and 49.83% (148/297), respectively. The top three pathogens were MP (16.52%), Flu B (7.83%) and RSV (6.41%). The total detection rate of respiratory pathogens in girls with acute respiratory tract infection was higher than that in boys (45.74% vs 34.19%) (於二 12.485, P<0,05). The detection rate of MP in girls was higher than that in boys (护二 5.409, P<0,05). The detection rate of Flu B and RSV in boys was higher than that in girls (X2=9.62& P<0.05)» There was significant difference in the total detection rate of respiratory pathogens among children of < 1-year-old group, 1-3-year-old group, and 4-6-year-old group with acute respiratory infection (25.28% vs 41.86% vs 65.60%) (X=141.142, P<0.05). The detection rate of MP, PIVS, Flu A, and Flu B gradually increased with the increase of age (X=32.099, 7.334, 6.317, and 17253, P<0.05). The detection rate of RSV decreased with the increase of age (X=7.443, P=0.024). The detection rate of ADV was the highest in the age group of 1 to 3 years old (於二 10.921, P<0.05)» The total detection rates of respiratory pathogens in children with acute respiratory tract infection in spring, summer, autumn, and winter were 32.24%, 37.71%, 41.86%, and 44.64%, respectively, and the difference was statistically significant - 8.608, P<0»05)» The detection rate of MP in winter was lower than that in other seasons (X=9.867, P<0.05), the detection rate of PIVS and RSV was the highest in spring, the detection rate of Flu A and ADV was the highest in winter, and the detection peak of Flu B was in spring and summer. The detection rate of mixed infection of respiratory pathogens in children with acute respiratory infection from 2019 to 2021 was 2.72% (250/920), and MP+RSV mixed infection was tlie most common type of double infection, with a detection rate of 10.87% (10/920). Conclusion There are many pathogens leading to acute respiratory infection in Shangrao city in 2019 and 2021, among which MP is the main respiratory pathogen, and pathogens have different epidemic characteristics in different genders, ages, and seasons. [ABSTRACT FROM AUTHOR]
نبذة مختصرة : 目的 分析2019--2021年上饶市某医疗机构急性呼吸道感染住院儿童常见病原体的流行特点, 为儿童急性呼吸 道感染防治工作提供相应依据。方法 收集2019--2021年在上饶市妇幼保健院就诊的920例急性呼吸道感染儿童的 血清样本,并采用间接免疫荧光法检测血清］gM抗体检测急性呼吸道感染常见病原体并进行统计分析。结果 急性呼 吸道感染病原体总检岀率38.91%(358/920),2019--2021年呼吸道病原体检岀率分别为28.26%(91/322)、39.53% (119/301).49.83%(148/297);检出率前三位病原体分别为 MP(16.52%)、FluB(7.83%)、RSV(6.41%)。女童急性呼吸道 感染患儿的呼吸道病原体总检出率高于男童(45.74% vs. 34.19%)(泻12.485,PV0.05),其中MP检出率女童高于男童 (於=5.409, Pv 0.05), FluB、RSV检岀率男童高于女童(f=9.628,6.224：P均v 0.05)。vl岁、1~3岁、4~6岁急性呼吸道 感染患儿的呼吸道病原体总检出率之间比较有统计学意义(25.28% vs. 41.86% vs. 65.60%)(泻141.142, PvO.05),其中 MP.PIVS.HuA.HuB检出率随着年龄的增长而逐渐增加(泻32.099、7.334、6.317、17.253,P均v 0.05),RSV检出率随着 年龄的增长而逐渐降低(泻7.443, 比0.024),ADV检出率在1 ~3岁组检出率最高(f = 10.921,P<0.05)o春季、夏季、秋 季、冬季急性呼吸道感染患儿的呼吸道病原体总检出率分别为32.24%、37.71%、41.86%、44.64%,差异有统计学意义 (f=8.608,P<0.05)o MP在冬季的检岀率低于其他季节(f=9.867,JP<0.05); PIVS.RSV均在春季检岀率最高;HuA.ADV 均在冬季检出率最高;FluB检出率高峰期在春、夏季。2019--2021年急性呼吸道感染患儿的呼吸道病原体混合感染检 出率为2.72%(25/920),双重感染以MP+RSV混合感染是最常见类型, 检岀率为10.87%(10/920)。结论 上饶市 2019-2021年存在多种导致患儿岀现急性呼吸道感染的病原体, 其中MP为主要呼吸道病原体,并且不同病原体在不 同性别、年龄、季节中具有一定流行特点. [ABSTRACT FROM AUTHOR]
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