نبذة مختصرة : This study was aimed to evaluate the oxidative stress status (malondialdehyde, MDA; catalase, CAT), metabolic status (beta hydroxybutyric acid, BHBA; nonesterified fatty acid NEFA) and hematological changes (hemoglobin, total leucocytes, red blood cells, neutrophils, platelets, lymphocytes) in serum of dairy cows before and after the surgical correction of left displacement abomasum. Twenty-six cows were divided into two groups as control (Group-A) and treatment (Group-B), each of 13 cows. Left displacement abomasum was confirmed by clinical assessment and ultrasonography, and then was surgically treated through Dirksen technique. Blood samples of both groups were collected on days 0, 7, 14, 21, and 28. Levels of various oxidative, metabolic and hematological parameters were measured by authenticated standard methods. We observed that serum levels of MDA and BHBA were higher at day 0 to day 14 (P<0.01), while the level of nonesterified fatty acid (NEFA) was higher at day 0 to day 7 (P<0.01) which dropped down to normal at day 21 (P>0.05) post-surgery in Group-B than Group-A. Moreover, CAT level in serum decreased (P<0.01) at day 0 to day 7, then it gradually increased to normal on day 14 to day 21 (P>0.05) post-surgery in Group B compared to Group A. In addition, levels of hemoglobin, total leucocytes, neutrophils were higher at day 0 to day 7 (P<0.01), while red blood cells and lymphocytes were lower at day 0 to day 14 (P<0.01) which became normal at day 28 (P>0.05) in Group-B than Group-A. The level of platelets was higher at day 0 (P<0.01), then gradually decreased to normal at day 28 in Group-B than Group-A. In conclusion, left displacement abomasum is associated with metabolic, oxidative and hematological disturbances which can be rectified through surgical correction. However, it is recommended to provide antioxidant therapy in adjunct with surgical correction for early recovery. [ABSTRACT FROM AUTHOR]
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