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Differences in the proportions of fluoroquinolone-resistant Gram-negative bacteria isolated from bacteraemic children with cancer in two Italian centres.
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- المؤلفون: Castagnola, E.1 ; Haupt, R.2; Micozzi, A.3; Caviglia, I.1; Testi, A. M.3; Giona, F.3; Parodi, S.2; Girmenia, C.2
- المصدر:
Clinical Microbiology & Infection. Jun2005, Vol. 11 Issue 6, p505-507. 3p.
- الموضوع:
- معلومة اضافية
- الموضوع:
- نبذة مختصرة :
The proportion of ciprofloxacin-resistant Gram-negative bacteria isolated from the blood of children with cancer (not receiving prophylaxis) was 10% in a paediatric hospital (Genoa) where the use of quinolones was highly restricted, compared with 41% in a department of haematology (Rome) where leukaemic adults, who received fluoroquinolone prophylaxis, were also treated (p < 0.0001). Moreover, simultaneous resistance to ciprofloxacin and ceftazidime, amikacin or imipenem–cilastatin was 11% in Genoa compared with 37% in Rome (p < 0.001). Ciprofloxacin resistance was more frequent in children who shared an environment with adults who were receiving ciprofloxacin prophylaxis. [ABSTRACT FROM AUTHOR]
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