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Gonadotrophin inhibitory hormone depresses gonadotrophin alpha and follicle-stimulating hormone beta subunit expression in the pituitary of the domestic chicken.
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- معلومة اضافية
- المصدر:
Publisher: Wiley & Sons Country of Publication: United States NLM ID: 8913461 Publication Model: Print Cited Medium: Print ISSN: 0953-8194 (Print) Linking ISSN: 09538194 NLM ISO Abbreviation: J Neuroendocrinol Subsets: MEDLINE
- بيانات النشر:
Publication: <2010->: Malden, MA : Wiley & Sons
Original Publication: Eynsham, Oxon, UK : Oxford University Press, c1989-
- الموضوع:
- نبذة مختصرة :
Studies performed in vitro suggest that a novel 12 amino acid RF amide peptide, isolated from the quail hypothalamus, is a gonadotrophin inhibitory hormone (GnIH). The aim of the present study was to investigate this hypothesis in the domestic chicken. Injections of GnIH into nest-deprived incubating hens failed to depress the concentration of plasma luteinizing hormone (LH). Addition of GnIH to short-term (120 min) cultures of diced pituitary glands from adult cockerels depressed follicle-stimulating hormone (FSH) and LH release and depressed common alpha and FSHbeta gonadotrophin subunit mRNAs, with no effect on LHbeta subunit mRNA. Hypothalamic GnIH mRNA was higher in incubating (out-of-lay) than in laying hens, but there was no significant difference in the amount of hypothalamic GnIH mRNA in out-of-lay and laying broiler breeder hens at the end of a laying year. It is concluded that avian GnIH may play a role in controlling gonadotrophin synthesis and associated constitutive release in the domestic chicken.
- الرقم المعرف:
0 (Avian Proteins)
0 (Follicle Stimulating Hormone, beta Subunit)
0 (Glycoprotein Hormones, alpha Subunit)
0 (Hypothalamic Hormones)
0 (RNA, Messenger)
0 (gonadotropin-inhibitory hormone, Coturnix japonica)
9002-67-9 (Luteinizing Hormone)
- الموضوع:
Date Created: 20050126 Date Completed: 20050613 Latest Revision: 20141120
- الموضوع:
20231215
- الرقم المعرف:
10.1111/j.1365-2826.2005.01260.x
- الرقم المعرف:
15667455
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