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Mitochondrial disease: Replace or edit?

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  • معلومة اضافية
    • الموضوع:
      ALLELES; MITOCHONDRIAL DNA; HAPLOTYPES; DIABETES; METABOLIC disorders
    • نبذة مختصرة :
      The article presents the discussion on maternal transmission of a wide spectrum of mutant alleles of mitochondrial DNA (mtDNA) giving rise to metabolic diseases. Topics include mitochondrial diseases being caused by mtDNA mutations while multiple mtDNA haplotypes coexist in cells called heteroplasmy; and showing supportive management of diabetes, deafness, and cardiac involvement.