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Estimation of intravoxel incoherent motion parameters using low b-values.
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- المؤلفون: Ye, Chen1; Xu, Daoyun1 ; Qin, Yongbin1; Wang, Lihui1; Wang, Rongpin2; Li, Wuchao2; Kuai, Zixiang3; Zhu, Yuemin4
- المصدر:
PLoS ONE. 2/6/2019, Vol. 14 Issue 2, p1-16. 16p.
- الموضوع:
- معلومة اضافية
- نبذة مختصرة :
Intravoxel incoherent motion (IVIM) imaging is a magnetic resonance imaging (MRI) technique widely used in clinical applications for various organs. However, IVIM imaging at low b-values is a persistent problem. This paper aims to investigate in a systematic and detailed manner how the number of low b-values influences the estimation of IVIM parameters. To this end, diffusion-weighted (DW) data with different low b-values were simulated to get insight into the distributions of subsequent IVIM parameters. Then, in vivo DW data with different numbers of low b-values and different number of excitations (NEX) were acquired. Finally, least-squares (LSQ) and Bayesian shrinkage prior (BSP) fitting methods were implemented to estimate IVIM parameters. The influence of the number of low b-values on IVIM parameters was analyzed in terms of relative error (RE) and structural similarity (SSIM). The results showed that the influence of the number of low b-values on IVIM parameters is variable. LSQ is more dependent on the number of low b-values than BSP, but the latter is more sensitive to noise. [ABSTRACT FROM AUTHOR]
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