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Inhaled nitric oxide (iNO) delivery with high-frequency jet ventilation (HFJV).

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  • المؤلفون: Platt DR;Platt DR; Swanton D; Blackney D
  • المصدر:
    Journal of perinatology : official journal of the California Perinatal Association [J Perinatol] 2003 Jul-Aug; Vol. 23 (5), pp. 387-91.
  • نوع النشر :
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 8501884 Publication Model: Print Cited Medium: Print ISSN: 0743-8346 (Print) Linking ISSN: 07438346 NLM ISO Abbreviation: J Perinatol Subsets: MEDLINE
    • بيانات النشر:
      Publication: 2001- : New York, NY : Nature Publishing Group
      Original Publication: [Philadelphia, Pa. : W.B. Saunders, c1984-
    • الموضوع:
      High-Frequency Jet Ventilation/*methods ; Nitric Oxide/*administration & dosage ; Respiratory Distress Syndrome, Newborn/*therapy; Administration, Inhalation ; Cohort Studies ; Combined Modality Therapy ; Female ; Humans ; Infant, Newborn ; Intubation, Intratracheal ; Male ; Prognosis ; Pulmonary Gas Exchange ; Respiratory Distress Syndrome, Newborn/diagnosis ; Respiratory Function Tests ; Risk Assessment ; Treatment Outcome
    • نبذة مختصرة :
      Objective: To determine if nitric oxide (NO) therapy can be reliably administered during high-frequency jet ventilation (HFJV) using the INOvent delivery system.
      Study Design: NO concentrations were measured just proximal to the endotracheal (ET) tube and at the distal tip of the ET tube during a bench evaluation. Measurements were taken over a wide range of airway pressure settings and NO concentrations with both high- and low- resistance lung models. Percent changes in set versus proximal and proximal versus distal iNO concentrations were tabulated.
      Results: Differences between proximal and distal NO concentrations were 10% or less. In the therapeutic range of up to 20 p.p.m., differences in concentration were 1 p.p.m. or less. There was no consistent effect on NO concentration when airway resistance was increased by 500%.
      Conclusion: Nitric oxide therapy can be reliably administered during HFJV with the INOvent delivery system when NO is injected exclusively via the HFJV circuit.
    • الرقم المعرف:
      31C4KY9ESH (Nitric Oxide)
    • الموضوع:
      Date Created: 20030709 Date Completed: 20030926 Latest Revision: 20131121
    • الموضوع:
      20240829
    • الرقم المعرف:
      10.1038/sj.jp.7210939
    • الرقم المعرف:
      12847534