Etiology of persistent tubo-ovarian abscess in Nairobi, Kenya.

Publisher: Hindawi Publishing Country of Publication: Egypt NLM ID: 9318481 Publication Model: Print Cited Medium: Print ISSN: 1064-7449 (Print) Linking ISSN: 10647449 NLM ISO Abbreviation: Infect Dis Obstet Gynecol Subsets: MEDLINE

Publication: <2006->: Cairo, Egypt : Hindawi Publishing
Original Publication: New York, NY : Wiley-Liss, c1993-

Abscess/*microbiology ; Oophoritis/*microbiology ; Pelvic Infection/*microbiology ; Salpingitis/*microbiology; Abscess/epidemiology ; Adult ; Bacteria, Anaerobic/isolation & purification ; Chronic Disease ; Cohort Studies ; Developing Countries ; Female ; Gram-Negative Bacteria/isolation & purification ; Gram-Positive Bacteria/isolation & purification ; Humans ; Incidence ; Kenya/epidemiology ; Oophoritis/epidemiology ; Pelvic Infection/epidemiology ; Pelvic Infection/etiology ; Recurrence ; Risk Assessment ; Salpingitis/epidemiology ; Severity of Illness Index ; Urban Population

Objective: To study the microbial etiology of tubo-ovarian abscess (TOA).
Methods: We recruited 11 women in Nairobi, Kenya who failed antibiotic therapy alone and required surgical drainage of a presumptive TOA. Pus from the nine abscesses and two pyosalpinges were collected and cultured for aerobic, facultative and anaerobic microorganisms.
Results: Eleven women suspected of having a TOA were hospitalized and treated for a median of 6 days (range 3-14 days) prior to surgical drainage of the abscess. Nine (82%) specimens were culture positive. Aerobes were present in all nine specimens. Seven of the nine positive cultures (78%) were polymicrobial and five of the polymicrobial cultures contained both anaerobes and aerobes. Anaerobic Gram-negative bacilli (Prevotella sp., Porphyromonas sp. and Bacteroides sp., Escherichia coli) and Streptococcus sp. (S. viridans and S. agalactiae) were the most common microorganisms isolated. Neisseria gonorrhoeae and Chlamydia trachomatis were not isolated by culture or detected by polymerase chain reaction.
Conclusions: In Kenya, persistent TOAs are associated with endogenous flora similar to that normally found in the gastrointestinal tract.

Am J Obstet Gynecol. 1999 Dec;181(6):1374-81. (PMID: 10601915)
Obstet Gynecol. 1968 Sep;32(3):382-6. (PMID: 5742119)
Am J Obstet Gynecol. 1975 Aug 1;122(7):891-901. (PMID: 167582)
J Natl Med Assoc. 1979 Nov;71(11):1109-11. (PMID: 529312)
Rev Infect Dis. 1983 Sep-Oct;5(5):876-84. (PMID: 6635426)
J Infect Dis. 1998 Nov;178(5):1352-8. (PMID: 9780255)
Ann Surg. 1993 Jun;217(6):624-32; discussion 632-3. (PMID: 8389537)
Clin Obstet Gynecol. 1993 Jun;36(2):433-44. (PMID: 8513637)
Am J Obstet Gynecol. 1995 Mar;172(3):919-25. (PMID: 7892886)
Am J Obstet Gynecol. 1996 Aug;175(2):435-41. (PMID: 8765265)
Clin Infect Dis. 1997 Feb;24(2):170-8. (PMID: 9114143)
J Infect Dis. 1988 Dec;158(6):1268-76. (PMID: 3058816)

Date Created: 20030704 Date Completed: 20030814 Latest Revision: 20181113

20231215

PMC1852266

10.1155/S1064744903000061

12839632