Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
Processing Request
Etiology and mode of presentation of chronic liver diseases in India: A multi centric study.
Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
Processing Request
- المؤلفون: Mukherjee, Partha S.1; Vishnubhatla, Sreenivas2; Amarapurkar, Deepak N.3; Das, Kausik4; Sood, Ajit5; Chawla, Yogesh K.6; Eapen, Chundamannil E.7; Boddu, Prabhakar8; Thomas, Varghese9; Varshney, Subodh10; Hidangmayum, Diamond Sharma11; Bhaumik, Pradip12; Thakur, Bhaskar2; Acharya, Subrat K.13; Chowdhury, Abhijit4,14
- المصدر:
PLoS ONE. 10/26/2017, Vol. 12 Issue 10, p1-13. 13p.
- الموضوع:
- معلومة اضافية
- الموضوع:
- نبذة مختصرة :
There is a paucity of health policy relevant data for chronic liver disease from India, impeding formulation of an interventional strategy to address the issue. A prospective, multicentric study to delineate the etiology and clinical profile of chronic liver disease in India is reported here. A centrally coordinated and monitored web-based data repository was developed (Feb, 2010 to Jan, 2013) and analyzed. Eleven hospitals from different parts of India participated. Data were uploaded into a web based proforma and monitored by a single centre according to a standardized protocol. 1.28% (n = 266621) of all patients (n = 20701383) attending the eleven participating hospitals of India had liver disease. 65807 (24·68%) were diagnosed for the first time (new cases). Of these, 13014 (19·77%, median age 43 years, 73% males) cases of chronic liver disease were finally analyzed. 33.9% presented with decompensated cirrhosis. Alcoholism (34·3% of 4413) was the commonest cause of cirrhosis while Hepatitis B (33·3%) was predominant cause of chronic liver disease in general and non-cirrhotic chronic liver disease (40·8% out of 8163). There was significant interregional differences (hepatitis C in North, hepatitis B in East and South, alcohol in North-east, Non-alcoholic Fatty Liver Disease in West) in the predominant cause of chronic liver disease. Hepatitis B (46·8% of 438 cases) was the commonest cause of hepatocellular Cancer.11·7% had diabetes. Observations of our study will help guide a contextually relevant liver care policy for India and could serve as a framework for similar endeavor in other developing countries as well. [ABSTRACT FROM AUTHOR]
No Comments.