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Central role of the P2Y[sub12] receptor in platelet activation.

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  • معلومة اضافية
    • نبذة مختصرة :
      Platelet activation occurs in response to vessel injury and is important for the arrest of bleeding. Platelet activation during disease states leads to vascular occlusion and ischemic damage. The P2Y[sub12] receptor, activated by ADP, plays a central role in platelet activation and is the target of P2Y[sub12] receptor antagonists that have proven therapeutic value. [ABSTRACT FROM AUTHOR]