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Do we need placebos to evaluate new drugs in children with schizophrenia?
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- المؤلفون: Armenteros JL;Armenteros JL; Mikhail AG
- المصدر:
Psychopharmacology [Psychopharmacology (Berl)] 2002 Jan; Vol. 159 (2), pp. 117-24. Date of Electronic Publication: 2001 Nov 20.
- نوع النشر :
Journal Article; Review
- اللغة:
English
- معلومة اضافية
- المصدر:
Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0033-3158 (Print) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE
- بيانات النشر:
Original Publication: Berlin, New York, Springer-Verlag.
- الموضوع:
- نبذة مختصرة :
Rationale: Ethical issues are raised when placebos are used in human experimentation. This ethical concern is accentuated when research is contemplated among special sub-groups such as children, especially if they suffer from schizophrenia.
Objectives: To review critically current ethical and scientific issues regarding the use of placebos in children with schizophrenia.
Methods: Manual review of literature and agency policies on pertinent issues and presentation of thoughtful original ideas as to the ethical use of placebos in children.
Results: There is compelling scientific and ethical justification underscoring the need and appropriateness of placebo-controlled studies in the treatment of childhood schizophrenia.
Conclusion: The authors believe that children will gain access to new medications and receive safe and optimal drug therapy through well-conducted research that employs placebo controls.
- Number of References:
46
- Contributed Indexing:
Indexing Agency: KIE Local ID #: 125960. Indexing Agency: NRCBL Local ID #: VF 18.3.
Keywords: Biomedical and Behavioral Research; Mental Health Therapies
Note: KIE Bib: human experimentation/mentally disabled; human experimentation/minors; human experimentation/research design
- الرقم المعرف:
0 (Placebos)
- الموضوع:
Date Created: 20020228 Date Completed: 20020402 Latest Revision: 20071115
- الموضوع:
20240627
- الرقم المعرف:
10.1007/s00213-001-0928-7
- الرقم المعرف:
11862338
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