Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Do we need placebos to evaluate new drugs in children with schizophrenia?

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • المؤلفون: Armenteros JL;Armenteros JL; Mikhail AG
  • المصدر:
    Psychopharmacology [Psychopharmacology (Berl)] 2002 Jan; Vol. 159 (2), pp. 117-24. Date of Electronic Publication: 2001 Nov 20.
  • نوع النشر :
    Journal Article; Review
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0033-3158 (Print) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Berlin, New York, Springer-Verlag.
    • الموضوع:
      Patient Selection*; Drug Evaluation/*methods ; Placebos/*therapeutic use ; Schizophrenia/*drug therapy; Child ; Controlled Clinical Trials as Topic/methods ; Controlled Clinical Trials as Topic/standards ; Drug Evaluation/standards ; Humans
    • نبذة مختصرة :
      Rationale: Ethical issues are raised when placebos are used in human experimentation. This ethical concern is accentuated when research is contemplated among special sub-groups such as children, especially if they suffer from schizophrenia.
      Objectives: To review critically current ethical and scientific issues regarding the use of placebos in children with schizophrenia.
      Methods: Manual review of literature and agency policies on pertinent issues and presentation of thoughtful original ideas as to the ethical use of placebos in children.
      Results: There is compelling scientific and ethical justification underscoring the need and appropriateness of placebo-controlled studies in the treatment of childhood schizophrenia.
      Conclusion: The authors believe that children will gain access to new medications and receive safe and optimal drug therapy through well-conducted research that employs placebo controls.
    • Number of References:
      46
    • Contributed Indexing:
      Indexing Agency: KIE Local ID #: 125960. Indexing Agency: NRCBL Local ID #: VF 18.3.
      Keywords: Biomedical and Behavioral Research; Mental Health Therapies
      Note: KIE Bib: human experimentation/mentally disabled; human experimentation/minors; human experimentation/research design
    • الرقم المعرف:
      0 (Placebos)
    • الموضوع:
      Date Created: 20020228 Date Completed: 20020402 Latest Revision: 20071115
    • الموضوع:
      20240627
    • الرقم المعرف:
      10.1007/s00213-001-0928-7
    • الرقم المعرف:
      11862338