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Risk Factors for Non-Adherence to cART in Immigrants with HIV Living in the Netherlands: Results from the ROtterdam ADherence (ROAD) Project.
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- المؤلفون: Been, Sabrina K.1 ; van de Vijver, David A. M. C.2; Nieuwkerk, Pythia T.3; Brito, Inês1; Stutterheim, Sarah E.4; Bos, Arjan E. R.4; Wolfers, Mireille E. G.5; Pogány, Katalin6; Verbon, Annelies1
- المصدر:
PLoS ONE. 10/5/2016, Vol. 11 Issue 10, p1-13. 13p.
- الموضوع:
- معلومة اضافية
- الموضوع:
- نبذة مختصرة :
In the Netherlands, immigrant people living with HIV (PLWH) have poorer psychological and treatment outcomes than Dutch PLWH. This cross-sectional field study examined risk factors for non-adherence to combination Antiretroviral Therapy (cART) among immigrant PLWH. First and second generation immigrant PLWH attending outpatient clinics at two HIV-treatment centers in Rotterdam were selected for this study. Socio-demographic and clinical characteristics for all eligible participants were collected from an existing database. Trained interviewers subsequently completed questionnaires together with consenting participants (n = 352) to gather additional data on socio-demographic characteristics, psychosocial variables, and self-reported adherence to cART. Univariable and multivariable logistic regression analyses were conducted among 301 participants who had used cART ≥6 months prior to inclusion. Independent risk factors for self-reported non-adherence were (I) not having attended formal education or only primary school (OR = 3.25; 95% CI: 1.28–8.26, versus University), (II) experiencing low levels of social support (OR = 2.56; 95% CI: 1.37–4.82), and (III) reporting low treatment adherence self-efficacy (OR = 2.99; 95% CI: 1.59–5.64). Additionally, HIV-RNA >50 copies/ml and internalized HIV-related stigma were marginally associated (P<0.10) with non-adherence (OR = 2.53; 95% CI: 0.91–7.06 and OR = 1.82; 95% CI: 0.97–3.43). The findings that low educational attainment, lack of social support, and low treatment adherence self-efficacy are associated with non-adherence point to the need for tailored supportive interventions. Establishing contact with peer immigrant PLWH who serve as role models might be a successful intervention for this specific population. [ABSTRACT FROM AUTHOR]
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