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Occupational asthma and contact dermatitis in a spray painter after introduction of an aziridine cross-linker.

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  • المؤلفون: Leffler CT;Leffler CT; Milton DK
  • المصدر:
    Environmental health perspectives [Environ Health Perspect] 1999 Jul; Vol. 107 (7), pp. 599-601.
  • نوع النشر :
    Case Reports; Clinical Conference; Journal Article
  • اللغة:
    English
  • معلومة اضافية
    • المصدر:
      Publisher: National Institute of Environmental Health Sciences Country of Publication: United States NLM ID: 0330411 Publication Model: Print Cited Medium: Print ISSN: 0091-6765 (Print) Linking ISSN: 00916765 NLM ISO Abbreviation: Environ Health Perspect Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Research Triangle Park, N. C. National Institute of Environmental Health Sciences.
    • الموضوع:
      Paint*; Asthma/*chemically induced ; Aziridines/*adverse effects ; Dermatitis, Contact/*etiology ; Occupational Diseases/*chemically induced; Adult ; Humans ; Male
    • نبذة مختصرة :
      A 23-year-old spray painter developed contact dermatitis and respiratory difficulty characterized by small airways obstruction shortly after the polyfunctional aziridine cross-linker CX-100 began to be used in his workplace as a paint activator. The symptoms resolved after he was removed from the workplace and was treated with inhaled and topical steroids. Painters may have an increased risk of asthma due to exposure to a variety of agents, such as isocyanates, alkyd resins, and chromates. This case illustrates the importance of using appropriate work practices and personal protective equipment to minimize exposure. Occupational asthma is diagnosed by a history of work-related symptoms and exposure to known causative agents. The diagnosis is confirmed by serial pulmonary function testing or inhalational challenge testing. The risk of asthma attributable to occupational exposures is probably underappreciated due to underreporting and to inappropriate use of narrow definitions of exposure in epidemiologic studies of attributable risk.
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    • الرقم المعرف:
      0 (Aziridines)
      54P5FEX9FH (aziridine)
    • الموضوع:
      Date Created: 19990624 Date Completed: 19990729 Latest Revision: 20181113
    • الموضوع:
      20250114
    • الرقم المعرف:
      PMC1566653
    • الرقم المعرف:
      10.1289/ehp.99107599
    • الرقم المعرف:
      10379008