نتائج البحث

Up-Regulation of the TRPM8 Channel Attenuates TRPC1-Mediated Store-Operated Calcium Entry in Abdominal Aortic Aneurysm.

• Authors : Wang YQ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fujian Medical University, Fuzhou 350122, China.; Key Laboratory of Fujian Province Universities on Ion Channel and Signal Transduction in Cardiovascular Diseases, Fujian Medical University, Fuzhou 350122, China.

Subjects: TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/metabolism ; TRPM Cation Channels*/TRPM Cation Channels*/TRPM Cation Channels*/genetics ; TRPC Cation Channels*/TRPC Cation Channels*/TRPC Cation Channels*/metabolism

• Source: Biomolecules [Biomolecules] 2026 May 19; Vol. 16 (5). Date of Electronic Publication: 2026 May 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

تفاصيل العنوان

Mechanisms by which sevoflurane affects cognitive function in aged marmosets and mice: up-regulation of FKBP5 expression in brain microglia.

• Authors : Zhang L; Department of Anesthesiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Anesthesiology, Shandong Provincial Key Medical and Health Laboratory of Anesthesia and Brain Function (The Affiliated Hospital of Qingdao University), The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.

Subjects: Sevoflurane*/Sevoflurane*/Sevoflurane*/pharmacology ; Tacrolimus Binding Proteins*/Tacrolimus Binding Proteins*/Tacrolimus Binding Proteins*/genetics ; Tacrolimus Binding Proteins*/Tacrolimus Binding Proteins*/Tacrolimus Binding Proteins*/metabolism

• Source: Medical gas research [Med Gas Res] 2026 Mar 01; Vol. 16 (1), pp. 19-25. Date of Electronic Publication: 2025 Apr 19.Publisher: STM Publishing Country of Publication: Australia NLM ID: 101564536 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

NPM1 mediated up - regulation of CXCR4 might drive bortezomib resistance in multiple Myeloma.

• Authors : Shi Y; Department of Hematology, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu Province, People's Republic of China.; Department of Hematology, The Huaian clinical college of Xuzhou Medical University, Xuzhou, Jiangsu Province, People's Republic of China.

Subjects: Receptors, CXCR4*/Receptors, CXCR4*/Receptors, CXCR4*/genetics ; Receptors, CXCR4*/Receptors, CXCR4*/Receptors, CXCR4*/biosynthesis ; Receptors, CXCR4*/Receptors, CXCR4*/Receptors, CXCR4*/metabolism

• Source: Hematology (Amsterdam, Netherlands) [Hematology] 2025 Dec; Vol. 30 (1), pp. 2565956. Date of Electronic Publication: 2025 Oct 25.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9708388 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

Up-regulation of Ifi27l2a expression in bone marrow monocytes contributes to glucocorticoid-induced bone loss.

• Authors : Wang Z; Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, China.; Huang C

Subjects: Monocytes*/Monocytes*/Monocytes*/metabolism ; Monocytes*/Monocytes*/Monocytes*/drug effects ; Glucocorticoids*/Glucocorticoids*/Glucocorticoids*/adverse effects

• Source: Communications biology [Commun Biol] 2025 Nov 17; Vol. 8 (1), pp. 1590. Date of Electronic Publication: 2025 Nov 17.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

Orai1 上调促进血管平滑肌钙化表型转化.

• Authors : 梁美英^1,2 ; 周维妍^1,2; 肖佩仪^1,2

• Source: Chinese Journal of Pathophysiology. May2026, Vol. 42 Issue 5, p843-851. 9p.

تفاصيل العنوان

Histone lactylation‐mediated up‐regulation of IGF2BP2 enhances ferroptosis resistance via Nrf2 in colorectal cancer

• Authors : Jin‐Feng Zhu; Da‐Peng Guo; Hai‐Na Lv

Subjects: Histones; Mice; NF-E2-Related Factor 2

• Source: Clin Transl Med

تفاصيل العنوان

IL-16 Up-Regulation is Associated with Epithelial Ovarian Cancer Progression and Poor Prognosis in Patients

• Authors : Lai, Huichao; Liao, Zhenrong; Liu, Jianying

Subjects: Ovarian Neoplasms; Adult; Interleukin-16

• Source: Clinical Medicine & Research. 23:3-10

تفاصيل العنوان

NFYA-Mediated TTK Up-Regulation Drives Fast Cell Cycle Progression and Its Inhibition Leads to Mitotic Catastrophe in Triple Negative Breast Cancer.

• Authors : Liu, Nianqiu^1,2 (AUTHOR) ; Zhu, Mengdi^1,2,3 (AUTHOR); Cai, Zijie^1,3 (AUTHOR)

• Source: Cancers. May2026, Vol. 18 Issue 9, p1324. 20p.

تفاصيل العنوان

Up Up-regulation of Soluble Programmed Death Ligand 1 (PD L1) Level as a Potential COVID-19 Severity-Associated Bio-parameter.

• Authors : Abbas, Zainab M.¹; Fadhil, Hula Y.¹

Subjects: *Programmed death-ligand 1; *COVID-19; *Disease progression

• Source: Iraqi Journal of Science. 2026, Vol. 67 Issue 4, p2198-2211. 14p.

تفاصيل العنوان

Linc00963 up-regulation alleviates postmenopausal osteoporosis through suppression of miR-506-3p.

• Authors : Li Q; The First Orthopedic Rehabilitation Center, Beijing Rehabilitation Hospital, Capital Medical University, Beijing, 100144, China.; Zhao J

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Osteoporosis, Postmenopausal*/Osteoporosis, Postmenopausal*/Osteoporosis, Postmenopausal*/genetics

• Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2025 Apr 11; Vol. 20 (1), pp. 367. Date of Electronic Publication: 2025 Apr 11.Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X

تفاصيل العنوان