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Unravelling the role of ubiquitin-specific proteases in breast carcinoma: insights into tumour progression and immune microenvironment modulation.

• Authors : Yang H; Qingdao Municipal Hospital Affiliated with Qingdao University, Qingdao, Shandong Province, 266011, China.; Sun T

Subjects: Tumor Microenvironment*/Tumor Microenvironment*/Tumor Microenvironment*/immunology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/immunology ; Breast Neoplasms*/Breast Neoplasms*/Breast Neoplasms*/pathology

• Source: World journal of surgical oncology [World J Surg Oncol] 2025 Feb 20; Vol. 23 (1), pp. 60. Date of Electronic Publication: 2025 Feb 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101170544 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7819

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Ubiquitin-specific proteases as key regulators in the malignant progression and therapy resistance of colorectal cancer: current insights and future perspectives

• Authors : Junyan Li; Shifan Deng; Wei Yu

Subjects: Ubiquitin-specific proteases; Deubiquitination; Colorectal cancer

• Source: Discover Oncology, Vol 16, Iss 1, Pp 1-20 (2025)

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Spotlights on ubiquitin-specific proteases in lung cancer: from multifaceted pathophysiological mechanisms to potential therapeutic targets

• Authors : Xiaoyun Shen; Ruoqi Wang; Fei Su

Subjects: Ubiquitin-specific proteases; Lung cancer; And deubiquitination

• Source: PeerJ, Vol 14, p e20702 (2026)

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Ubiquitin-specific proteases in hepatitis: bridging molecular mechanisms and therapeutic potential

• Authors : Kavita Goyal; Muhammad Afzal; Ashok Kumar Bishoyi

Subjects: Ubiquitin-specific proteases; RD1-811; Clinical outcomes

• Source: Egyptian Liver Journal, Vol 15, Iss 1, Pp 1-18 (2025)

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Ubiquitin-specific proteases (USPs) in leukemia: a systematic review.

• Authors : Zangooie A; Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran.; Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran.

Subjects: Leukemia*/Leukemia*/Leukemia*/pathology ; Leukemia*/Leukemia*/Leukemia*/enzymology ; Leukemia*/Leukemia*/Leukemia*/diagnosis

• Source: BMC cancer [BMC Cancer] 2024 Jul 25; Vol. 24 (1), pp. 894. Date of Electronic Publication: 2024 Jul 25.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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USP34 modulates mitochondrial function in triple-negative breast cancer cells through the eIf3m/MTCH2 axis.

• Authors : Qian PF; Department of Breast Surgery, Huizhou Third People's Hospital, Affiliated Hospital of Guangzhou Medical University, Huizhou, Guangdong, China.; Zeng Y

Subjects: Eukaryotic Initiation Factor-3*/Eukaryotic Initiation Factor-3*/Eukaryotic Initiation Factor-3*/metabolism ; Eukaryotic Initiation Factor-3*/Eukaryotic Initiation Factor-3*/Eukaryotic Initiation Factor-3*/genetics ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism

• Source: Journal of histotechnology [J Histotechnol] 2026 Jun; Vol. 49 (2), pp. 113-125. Date of Electronic Publication: 2026 Apr 23.Publisher: Historical Metallurgy Society Country of Publication: England NLM ID: 8003807 Publication Model: Print-Electronic Cited Medium: Internet

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Ubiquitin-Specific Protease 45 Inhibits Lung Adenocarcinoma Ferroptosis by Regulating Ubiquitination and Stability of Glutathione Peroxidase 4.

• Authors : Huang M; Fujian Medical University Clinical Teaching Hospital, Fuzhou, China.; Department of Laboratory, Fuzhou Pulmonary Hospital of Fujian, Fuzhou, China.

Subjects: Ferroptosis*/Ferroptosis*/Ferroptosis*/genetics ; Phospholipid Hydroperoxide Glutathione Peroxidase*/Phospholipid Hydroperoxide Glutathione Peroxidase*/Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism ; Phospholipid Hydroperoxide Glutathione Peroxidase*/Phospholipid Hydroperoxide Glutathione Peroxidase*/Phospholipid Hydroperoxide Glutathione Peroxidase*/genetics

• Source: Cancer medicine [Cancer Med] 2026 May; Vol. 15 (5), pp. e71901.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN:

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Deubiquitinating Enzymes Ubiquitin-Specific Proteases 7 and 10 Regulate TAU Aggregation.

• Authors : Volbracht, Christiane¹ (AUTHOR) ; Fog, Karina¹ (AUTHOR)

• Source: International Journal of Molecular Sciences. Nov2025, Vol. 26 Issue 22, p11062. 24p.

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Drug resistance mechanisms and treatment strategies mediated by Ubiquitin-Specific Proteases (USPs) in cancers: new directions and therapeutic options.

• Authors : Gao H; Department of Oncology, Shengjing Hospital of China Medical University, Shenyang, 110004, China.; Xi Z

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/pathology

• Source: Molecular cancer [Mol Cancer] 2024 May 03; Vol. 23 (1), pp. 88. Date of Electronic Publication: 2024 May 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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USP39 promotes antiviral defense through post-transcriptional control of RIG-I and stabilization of STING.

• Authors : Quan J; Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation, Marshall Laboratory of Biomedical Engineering, Institute of Biological Therapy, Shenzhen University Medical School, Shenzhen University, Shenzhen, China.; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, China.

Subjects: Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/metabolism ; Membrane Proteins*/Membrane Proteins*/Membrane Proteins*/genetics ; DEAD Box Protein 58*/DEAD Box Protein 58*/DEAD Box Protein 58*/metabolism

• Source: PLoS biology [PLoS Biol] 2026 May 11; Vol. 24 (5), pp. e3003796. Date of Electronic Publication: 2026 May 11 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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