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  • 1-10 ل  69,927 نتائج ل ""Proto-Oncogene Proteins""

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Academic Journal

Saikosaponin A Recovers Impaired Filaggrin Levels in Inflamed Skin by Downregulating the Expression of FRA1 and c-Jun.

  • Authors : Ahn SS; Department of Biological Sciences, Sanghuh College of Lifesciences, Konkuk University, Seoul 05029, Republic of Korea.; Yeo H

Subjects: Filaggrin Proteins* ; Oleanolic Acid*/Oleanolic Acid*/Oleanolic Acid*/analogs & derivatives ; Oleanolic Acid*/Oleanolic Acid*/Oleanolic Acid*/pharmacology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Aug 27; Vol. 29 (17). Date of Electronic Publication: 2024 Aug 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Combination of arsenic trioxide and apatinib synergistically inhibits small cell lung cancer by down-regulating VEGFR2/mTOR and Akt/c-Myc signaling pathway via GRB10.

  • Authors : Yu Y; Harbin Medical University, Harbin, Heilongjiang Province, China.; Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China.

Subjects: Arsenic Trioxide*/Arsenic Trioxide*/Arsenic Trioxide*/therapeutic use ; Arsenic Trioxide*/Arsenic Trioxide*/Arsenic Trioxide*/pharmacology ; Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/Vascular Endothelial Growth Factor Receptor-2*/genetics

  • Source: Hereditas [Hereditas] 2024 Sep 02; Vol. 161 (1), pp. 29. Date of Electronic Publication: 2024 Sep 02.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 0374654 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

SFRP4 promotes autophagy and blunts FSH responsiveness through inhibition of AKT signaling in ovarian granulosa cells.

  • Authors : Bérubé M; Centre de Recherche en Reproduction et Fertilité, Faculté de Médecine Vétérinaire, Université de Montréal, 3200 rue Sicotte, St-Hyacinthe, QC, J2S 2M2, Canada.; Abedini A

Subjects: Granulosa Cells*/Granulosa Cells*/Granulosa Cells*/metabolism ; Granulosa Cells*/Granulosa Cells*/Granulosa Cells*/drug effects ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Aug 14; Vol. 22 (1), pp. 396. Date of Electronic Publication: 2024 Aug 14.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

Loss of Heterozygosity and Mutations in the RAS-ERK Pathway Genes in Tumor Cells of Various Loci in Multiple Myeloma.

  • Authors : Soloveva M; National Medical Research Center for Hematology, Novy Zykovski Lane, 4a, 125167 Moscow, Russia.; Solovev M

Subjects: Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/genetics ; Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/pathology ; Mutation*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 30; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Dual inhibition of SUMOylation and MEK conquers MYC-expressing KRAS-mutant cancers by accumulating DNA damage.

  • Authors : Kotani H; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, 13-1 Takara-Machi, Kanazawa, Ishikawa, 920-0934, Japan. .; Oshima H

Subjects: Sumoylation*/Sumoylation*/Sumoylation*/drug effects ; DNA Damage*/DNA Damage*/DNA Damage*/drug effects ; Proto-Oncogene Proteins p21(ras)*/Proto-Oncogene Proteins p21(ras)*/Proto-Oncogene Proteins p21(ras)*/genetics

  • Source: Journal of biomedical science [J Biomed Sci] 2024 Jul 11; Vol. 31 (1), pp. 68. Date of Electronic Publication: 2024 Jul 11.Publisher: BioMed Central Country of Publication: England NLM ID: 9421567 Publication Model: Electronic Cited Medium: Internet ISSN: 1423-0127

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Academic Journal

Polyamine and EIF5A hypusination downstream of c-Myc confers targeted therapy resistance in BRAF mutant melanoma.

  • Authors : Park BS; Medicinal Materials Research Center, Korea Institute of Science and Technology, 5 Hwarangro-14-Gil, SeongbukGu, Seoul, 02792, Republic of Korea.; Department of Life Sciences, Korea University, 145 AnamRo, SeongbukGu, Seoul, 02841, Republic of Korea.

Subjects: Melanoma*/Melanoma*/Melanoma*/drug therapy ; Melanoma*/Melanoma*/Melanoma*/genetics ; Melanoma*/Melanoma*/Melanoma*/metabolism

  • Source: Molecular cancer [Mol Cancer] 2024 Jul 04; Vol. 23 (1), pp. 136. Date of Electronic Publication: 2024 Jul 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Regulation of RAF family kinases: new insights from recent structural and biochemical studies.

  • Authors : Spencer-Smith R; Laboratory of Cell and Developmental Signaling, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD 21702, U.S.A.; Morrison DK

Subjects: HSP90 Heat-Shock Proteins*/HSP90 Heat-Shock Proteins*/HSP90 Heat-Shock Proteins*/metabolism ; HSP90 Heat-Shock Proteins*/HSP90 Heat-Shock Proteins*/HSP90 Heat-Shock Proteins*/chemistry ; Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/Proto-Oncogene Proteins B-raf*/metabolism

  • Source: Biochemical Society transactions [Biochem Soc Trans] 2024 Jun 26; Vol. 52 (3), pp. 1061-1069.Publisher: Portland Press On The Behalf Of The Biochemical Society Country of Publication: England NLM ID: 7506897 Publication Model: Print Cited Medium:

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Editorial & Opinion

Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor.

  • Authors : Shi ZY; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Fang Y

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/therapeutic use ; Proto-Oncogene Proteins c-bcl-2*/Proto-Oncogene Proteins c-bcl-2*/Proto-Oncogene Proteins c-bcl-2*/genetics

  • Source: Clinical and translational medicine [Clin Transl Med] 2024 Jun; Vol. 14 (6), pp. e1691.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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Academic Journal

Targeting Hdm2 and Hdm4 in Anticancer Drug Discovery: Implications for Checkpoint Inhibitor Immunotherapy.

  • Authors : Ntwasa M; Department of Life and Consumer Sciences, University of South Africa, Cnr Pioneer Road and Christiaan de Wet Road, Florida, Johannesburg 1710, South Africa.

Subjects: Proto-Oncogene Proteins c-mdm2*/Proto-Oncogene Proteins c-mdm2*/Proto-Oncogene Proteins c-mdm2*/metabolism ; Proto-Oncogene Proteins c-mdm2*/Proto-Oncogene Proteins c-mdm2*/Proto-Oncogene Proteins c-mdm2*/antagonists & inhibitors ; Immunotherapy*/Immunotherapy*/Immunotherapy*/methods

  • Source: Cells [Cells] 2024 Jun 29; Vol. 13 (13). Date of Electronic Publication: 2024 Jun 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

WISP-1 Regulates Cardiac Fibrosis by Promoting Cardiac Fibroblasts' Activation and Collagen Processing.

  • Authors : Li Z; Translational Health Sciences, Bristol Medical School, University of Bristol, Research Floor Level 7, Bristol Royal Infirmary, Bristol BS2 8HW, UK.; Williams H

Subjects: CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/metabolism ; CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/CCN Intercellular Signaling Proteins*/genetics ; Fibroblasts*/Fibroblasts*/Fibroblasts*/metabolism

  • Source: Cells [Cells] 2024 Jun 06; Vol. 13 (11). Date of Electronic Publication: 2024 Jun 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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  • 1-10 ل  69,927 نتائج ل ""Proto-Oncogene Proteins""