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Navození indukce CYP3A4 metamizolem potvrzené metodou TDM: případová studie s kvetiapinem.

• Authors : Tašková, Ivana^1,2

• Source: Klinická Farmakologie a Farmacie. Dec2025, Vol. 39 Issue 4, p213-217. 5p.

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Impact of CYP3A4 rs2242480 Gene Polymorphism on Rivaroxaban Plasma Level Concentration and Bleeding Risks among Iraqi Patients with Atrial Fibrillation

• Authors : Mohammed Radhi Abbas; Mazin Hamid Ouda; Suzanne Jubair Abbas

• Source: Karbala Journal of Pharmaceutical Sciences. 16:308-317

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Correlations between 4 beta-hydroxycholesterol and hepatic and intestinal CYP3A4: protein expression, microsomal ex vivo activity, and in vivo activity in patients with a wide body weight range

• Authors : Kvitne, Kine Eide, Author; Hole, Kristine, Author; Krogstad, Veronica, Author ...

Subjects: 4 beta-Hydroxycholesterol; CYP3A4; Midazolam pharmacokinetics

• Source: European Journal of Clinical Pharmacology. 78(8):1289-1299

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Impact of CYP3A4 rs2242480 Gene Polymorphism on Rivaroxaban Plasma Level Concentration and Bleeding Risks among Iraqi Patients with Atrial Fibrillation.

• Authors : Abbas, Mohammed Radhi¹ ; Ouda, Mazin Hamid¹; Abbas, Suzanne Jubair¹

Subjects: *Cytochrome P-450 CYP3A; *Rivaroxaban; *Iraqis

• Source: Karbala Journal of Pharmaceutical Sciences. Nov2025, Vol. 16 Issue 27, p290-317. 28p.

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Enhancing CYP3A4 Inhibition Prediction Using a Hybrid GNN–ML Model with Data Augmentation.

• Authors : Woo, Somin^1,2,3 (AUTHOR); Jeon, Ju-Hyeok^2,4 (AUTHOR); Han, Sangil^3,5 (AUTHOR)

• Source: Pharmaceuticals (14248247). Feb2026, Vol. 19 Issue 2, p258. 20p.

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New Insights into Prostate Cancer Susceptibility in European Caucasians: A Systematic Review and Meta-Analysis of CYP3A4 Pharmacogene.

• Authors : Pagoni, Maria¹ (AUTHOR) ; Cava, Claudia² (AUTHOR); Tsangaris, George T.³ (AUTHOR)

• Source: Cancers. Jan2026, Vol. 18 Issue 1, p58. 18p.

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LRRC8A Inhibition Overcomes Chemoresistance by Downregulating MRP3 and CYP3A4 in the 3D Spheroid Model of Human Breast Cancer Cells.

• Authors : Otsuka, Ryo¹ (AUTHOR); Kajikuri, Junko^1,2 (AUTHOR); Matsui, Miki¹ (AUTHOR)

• Source: International Journal of Molecular Sciences. Mar2026, Vol. 27 Issue 6, p2646. 27p.

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Application of Physiologically‐Based Pharmacokinetic Modeling to Support Drug Labeling: Prediction of CYP3A4 ‐Mediated Pirtobrutinib‐Drug Interactions

• Authors : Dan‐Dan Tian; Stephen D. Hall; Sonya C. Chapman

Subjects: Male; Adult; Research

• Source: CPT Pharmacometrics Syst Pharmacol

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Evaluation of Drug–Drug Interaction Potential Between the Oral Antibiotic Zoliflodacin and the CYP3A4 Inhibitor Itraconazole: A Phase 1 Study in Healthy Participants.

• Authors : Luckey, Alison¹ (AUTHOR) ; Larson, Kajal B.² (AUTHOR); Rayad, Noha³ (AUTHOR)

• Source: CTS: Clinical & Translational Science. Mar2026, Vol. 19 Issue 3, p1-9. 9p.

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Evaluation of Vamorolone CYP3A4 Induction on Midazolam (a Sensitive CYP 3A4 Substrate) Pharmacokinetics

• Source: An Open-label, Single-arm Study to Evaluate the CYP3A4 Induction Potential of Vamorolone on the Pharmacokinetics of Midazolam (a Sensitive

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