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Academic Journal

Opioid-based versus opioid-sparing patient-controlled analgesia using ketorolac and nefopam after total knee arthroplasty: a randomized, double-blind, non-inferiority trial.

Authors : Han J; Department of Anesthesiology and Pain Medicine, Chung-Ang University Gwangmyeong Hospital, Chung-Ang University College of Medicine, Gwangmyeong, Korea.; Jung H

Subjects: Arthroplasty, Replacement, Knee*/Arthroplasty, Replacement, Knee*/Arthroplasty, Replacement, Knee*/adverse effects ; Arthroplasty, Replacement, Knee*/Arthroplasty, Replacement, Knee*/Arthroplasty, Replacement, Knee*/trends ; Nefopam*/Nefopam*/Nefopam*/administration & dosage

Source: Korean journal of anesthesiology [Korean J Anesthesiol] 2026 Apr; Vol. 79 (2), pp. 213-223. Date of Electronic Publication: 2026 Feb 03.Publisher: Korean Society of Anesthesiologists Country of Publication: Korea (South) NLM ID: 101502451 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Opioid Signaling in Multiple Sclerosis: Emerging Targets for Repair.

Authors : Perlikowska R; Department of Nucleic Acid Biochemistry, Medical University of Lodz, Pomorska 251, 92-213 Lodz, Poland.; Domowicz M

Subjects: Multiple Sclerosis*/Multiple Sclerosis*/Multiple Sclerosis*/metabolism ; Multiple Sclerosis*/Multiple Sclerosis*/Multiple Sclerosis*/drug therapy ; Multiple Sclerosis*/Multiple Sclerosis*/Multiple Sclerosis*/pathology

Source: International journal of molecular sciences [Int J Mol Sci] 2026 May 05; Vol. 27 (9). Date of Electronic Publication: 2026 May 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Tapentadol-induced urticarial rash in a patient with acute pancreatitis.

Authors : Deshidi S; Department of Gastroenterology, Krishna Institute of Medical Sciences, Secunderabad, Telangana, India.; Hanumanthu V

Subjects: Pancreatitis*/Pancreatitis*/Pancreatitis*/drug therapy ; Urticaria*/Urticaria*/Urticaria*/chemically induced ; Urticaria*/Urticaria*/Urticaria*/drug therapy

Source: Indian journal of pharmacology [Indian J Pharmacol] 2026 May 01; Vol. 58 (3), pp. 276-279. Date of Electronic Publication: 2026 May 01.Publisher: Medknow Publications Country of Publication: India NLM ID: 7902477 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Criterion validity and divergent risk profiles of long-term opioid therapy across medicare and medicaid.

Authors : Hurley RW; Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, United States of America.; Department of Translational Neuroscience, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, United States of America.

Subjects: Medicaid*/Medicaid*/Medicaid*/statistics & numerical data ; Analgesics, Opioid*/Analgesics, Opioid*/Analgesics, Opioid*/therapeutic use ; Analgesics, Opioid*/Analgesics, Opioid*/Analgesics, Opioid*/adverse effects

Source: PloS one [PLoS One] 2026 Apr 29; Vol. 21 (4), pp. e0347943. Date of Electronic Publication: 2026 Apr 29 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Kratom (Mitragyna speciosa) as a Phytochemical-Based Natural Product Exhibiting Opioid-like Analgesic Effects with Reduced Tolerance and Dependence Liability via TLR4-Associated Neuroimmune Modulation.

Authors : Prasetya F; Faculty of Pharmacy, University of Mulawarman, Samarinda 75119, Indonesia.; Indriyanti N

Subjects: Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/metabolism ; Toll-Like Receptor 4*/Toll-Like Receptor 4*/Toll-Like Receptor 4*/chemistry ; Mitragyna*/Mitragyna*/Mitragyna*/chemistry

Source: Molecules (Basel, Switzerland) [Molecules] 2026 Apr 26; Vol. 31 (9). Date of Electronic Publication: 2026 Apr 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Association between gabapentinoid treatment, concurrent use with opioid or benzodiazepine and the risk of drug poisoning: A self-controlled case series study.

Authors : Yuen ASC; Research Department of Practice and Policy, School of Pharmacy, University College London, London, United Kingdom.; Centre for Medicines Optimisation Research and Education, University College London Hospitals NHS Foundation Trust, London, United Kingdom.

Subjects: Benzodiazepines*/Benzodiazepines*/Benzodiazepines*/poisoning ; Benzodiazepines*/Benzodiazepines*/Benzodiazepines*/adverse effects ; Analgesics, Opioid*/Analgesics, Opioid*/Analgesics, Opioid*/poisoning

Source: PLoS medicine [PLoS Med] 2026 Apr 16; Vol. 23 (4), pp. e1005035. Date of Electronic Publication: 2026 Apr 16 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101231360 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Association between early methadone dose titration and treatment discontinuation and opioid toxicity: A retrospective cohort study.

Authors : Garg R; ICES, Toronto, Ontario, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.

Subjects: Methadone*/Methadone*/Methadone*/administration & dosage ; Methadone*/Methadone*/Methadone*/adverse effects ; Analgesics, Opioid*/Analgesics, Opioid*/Analgesics, Opioid*/adverse effects

Source: PLoS medicine [PLoS Med] 2026 Apr 09; Vol. 23 (4), pp. e1004748. Date of Electronic Publication: 2026 Apr 09 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101231360 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Review of Structural Modification and Development of Novel Tramadol Derivatives.

Authors : Wang N; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China.; Zhou X

Subjects: Tramadol*/Tramadol*/Tramadol*/chemistry ; Tramadol*/Tramadol*/Tramadol*/pharmacology ; Tramadol*/Tramadol*/Tramadol*/analogs & derivatives

Source: Molecules (Basel, Switzerland) [Molecules] 2026 Apr 02; Vol. 31 (7). Date of Electronic Publication: 2026 Apr 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Comparison of Analgesic Efficacy of Intrathecal Morphine and Ultrasound-Guided Bilateral Erector Spinae Plane Block in Patients Undergoing Open Heart Surgery with Midline Sternotomy: An Open Label Randomized Control Trial.

Authors : Karuppiah V; Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.; Kumar R

Subjects: Morphine*/Morphine*/Morphine*/administration & dosage ; Morphine*/Morphine*/Morphine*/therapeutic use ; Postoperative Pain*/Postoperative Pain*/Postoperative Pain*/drug therapy

Source: Annals of cardiac anaesthesia [Ann Card Anaesth] 2026 Apr 01; Vol. 29 (2), pp. 212-218. Date of Electronic Publication: 2026 Apr 15.Publisher: Medknow Country of Publication: India NLM ID: 9815987 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0974-5181

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Academic Journal

Pain and treatment outcomes after initiating methadone vs buprenorphine among medicare patients with opioid use disorder and comorbid chronic pain: A target trial emulation.

Authors : Wei YJ; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America.; Winterstein AG

Subjects: Methadone*/Methadone*/Methadone*/therapeutic use ; Methadone*/Methadone*/Methadone*/adverse effects ; Buprenorphine*/Buprenorphine*/Buprenorphine*/therapeutic use

Source: PLoS medicine [PLoS Med] 2026 Mar 26; Vol. 23 (3), pp. e1004846. Date of Electronic Publication: 2026 Mar 26 (Print Publication: 2026).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101231360 Publication Model: eCollection Cited Medium: Internet

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فلترة النتائج

Opioid-based versus opioid-sparing patient-controlled analgesia using ketorolac and nefopam after total knee arthroplasty: a randomized, double-blind, non-inferiority trial.

Opioid Signaling in Multiple Sclerosis: Emerging Targets for Repair.

Tapentadol-induced urticarial rash in a patient with acute pancreatitis.

Criterion validity and divergent risk profiles of long-term opioid therapy across medicare and medicaid.

Kratom (Mitragyna speciosa) as a Phytochemical-Based Natural Product Exhibiting Opioid-like Analgesic Effects with Reduced Tolerance and Dependence Liability via TLR4-Associated Neuroimmune Modulation.

Association between gabapentinoid treatment, concurrent use with opioid or benzodiazepine and the risk of drug poisoning: A self-controlled case series study.

Association between early methadone dose titration and treatment discontinuation and opioid toxicity: A retrospective cohort study.

Review of Structural Modification and Development of Novel Tramadol Derivatives.

Comparison of Analgesic Efficacy of Intrathecal Morphine and Ultrasound-Guided Bilateral Erector Spinae Plane Block in Patients Undergoing Open Heart Surgery with Midline Sternotomy: An Open Label Randomized Control Trial.

Pain and treatment outcomes after initiating methadone vs buprenorphine among medicare patients with opioid use disorder and comorbid chronic pain: A target trial emulation.

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