نتائج البحث

Antifibrotic Effects of Thymus syriacus Essential Oil in Bleomycin-Induced Pulmonary Fibrosis via Suppression of the TGF-β1/Smad2 Axis.

• Authors : Aksoy P; Department of Biology, Faculty of Science, Gaziantep University, 27010 Gaziantep, Turkey.; Yumrutaş Ö

Subjects: Bleomycin*/Bleomycin*/Bleomycin*/adverse effects ; Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/metabolism ; Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/Transforming Growth Factor beta1*/genetics

• Source: International journal of molecular sciences [Int J Mol Sci] 2026 Jan 30; Vol. 27 (3). Date of Electronic Publication: 2026 Jan 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Molecular Mechanisms of Pulmonary Fibrosis: The Interaction of Epithelial-mesenchymal Transition and AMPK Pathways in a Bleomycin-induced Model.

• Authors : Sadatpour O; Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran AND Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran. .; Kavosi H

Subjects: AMP-Activated Protein Kinases*/AMP-Activated Protein Kinases*/AMP-Activated Protein Kinases*/metabolism ; Pulmonary Fibrosis*/Pulmonary Fibrosis*/Pulmonary Fibrosis*/metabolism ; Pulmonary Fibrosis*/Pulmonary Fibrosis*/Pulmonary Fibrosis*/pathology

• Source: Iranian journal of allergy, asthma, and immunology [Iran J Allergy Asthma Immunol] 2026 Jan 01; Vol. 25 (1), pp. 80-92. Date of Electronic Publication: 2026 Jan 01.Publisher: Tehran University of Medical Sciences Country of Publication: Iran NLM ID: 101146178 Publication Model: Electronic Cited Medium: Internet

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Inhaled Angiopoietin-Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis.

• Authors : Fan H; Department of Otolaryngology, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, P. R. China.; Department of Thoracic Surgery, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, P. R. China.

Subjects: Angiopoietin-Like Protein 4*/Angiopoietin-Like Protein 4*/Angiopoietin-Like Protein 4*/genetics ; Angiopoietin-Like Protein 4*/Angiopoietin-Like Protein 4*/Angiopoietin-Like Protein 4*/metabolism ; Oligonucleotides, Antisense*/Oligonucleotides, Antisense*/Oligonucleotides, Antisense*/administration & dosage

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Apr; Vol. 13 (23), pp. e01909. Date of Electronic Publication: 2026 Mar 23.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Possible Protective Role of Pirfenidone Versus Combined Antifibrotic Therapy Colchicine and Pirfenidone in a Rat Model of Bleomycin Induced Pulmonary Fibrosis and Evaluation of their Potential Impact on α-SMA, IL6 and TGFβ (Histological and Immunohistochemical Study)

• Authors : Abdelmoez, Walaa Adel¹

• Source: Egyptian Journal of Histology. Mar2024, Vol. 47 Issue 1, p238-252. 15p.

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Echinacea purpurea ameliorates Bleomycin-induced pulmonary fibrosis in rats through modulating NADPH oxidase-4 and endothelin-1/connective tissue growth factor/matrix metalloproteinases signalling axis.

• Authors : Salama AAA; Pharmacology Department, Medical Research and Clinical Studies Institute, National Research Centre (ID: 60014618), 33 ELBohouth St. (former EL Tahrir St.), P.O. 12622, Dokki, Cairo, Egypt.; Elgohary R

Subjects: Bleomycin*/Bleomycin*/Bleomycin*/adverse effects ; Connective Tissue Growth Factor*/Connective Tissue Growth Factor*/Connective Tissue Growth Factor*/metabolism ; NADPH Oxidase 4*/NADPH Oxidase 4*/NADPH Oxidase 4*/metabolism

• Source: Scientific reports [Sci Rep] 2025 Sep 02; Vol. 15 (1), pp. 32332. Date of Electronic Publication: 2025 Sep 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Improvement of Number 2 Feibi Recipe on pulmonary fibrosis in mice by inhibiting the level of miR-199a-5p and activating autophagy.

• Authors : Li Z; Graduate school, Beijing University of Chinese Medicine, Beijing, China.; Liu Z

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; MicroRNAs*/MicroRNAs*/MicroRNAs*/antagonists & inhibitors

• Source: Scientific reports [Sci Rep] 2025 Dec 17; Vol. 15 (1), pp. 44020. Date of Electronic Publication: 2025 Dec 17.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Nuclear accumulated µ-calpain enhances FoxO3a phosphorylation in AT2 cell and exacerbates pulmonary fibrosis.

• Authors : Li Q; Department of Respiratory and Critical Care Medicine, Xijing Hospital, Xi'an, China.; Department of Thoracic Surgery, Tianshui First-People's Hospital, Tian'shui, China.

Subjects: Calpain*/Calpain*/Calpain*/metabolism ; Forkhead Box Protein O3*/Forkhead Box Protein O3*/Forkhead Box Protein O3*/metabolism ; Pulmonary Fibrosis*/Pulmonary Fibrosis*/Pulmonary Fibrosis*/metabolism

• Source: Experimental lung research [Exp Lung Res] 2025 Nov 03; Vol. 51 (1), pp. 138-156. Date of Electronic Publication: 2025 Nov 09.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8004944 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Integration of pharmacodynamics, network pharmacology and metabolomics to elucidate the effect and mechanism of Jingfang Granule in the treatment of Paraquat induced Pulmonary fibrosis.

• Authors : Yue R; State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co. Ltd, Linyi, China.; Yang T

Subjects: Paraquat*/Paraquat*/Paraquat*/toxicity ; Pulmonary Fibrosis*/Pulmonary Fibrosis*/Pulmonary Fibrosis*/drug therapy ; Pulmonary Fibrosis*/Pulmonary Fibrosis*/Pulmonary Fibrosis*/chemically induced

• Source: PloS one [PLoS One] 2025 Feb 18; Vol. 20 (2), pp. e0318246. Date of Electronic Publication: 2025 Feb 18 (Print Publication: 2025).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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IQGAP1 Regulates Actin Polymerization and Contributes to Bleomycin-Induced Lung Fibrosis.

• Authors : Akter T; Department of Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 912, Charleston, SC 29425, USA.; Atanelishvili I

Subjects: Actins*/Actins*/Actins*/metabolism ; Fibroblasts*/Fibroblasts*/Fibroblasts*/metabolism ; Fibroblasts*/Fibroblasts*/Fibroblasts*/pathology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 11; Vol. 25 (10). Date of Electronic Publication: 2024 May 11.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Pirfenidone combined with UC-MSCs reversed bleomycin-induced pulmonary fibrosis.

• Authors : Xu J; Department of Respiratory and Critical Care Medicine, First People's Hospital of Kashi, Kashi, China.; Abudureheman Z

Subjects: Pyridones*/Pyridones*/Pyridones*/pharmacology ; Pyridones*/Pyridones*/Pyridones*/therapeutic use ; Bleomycin*/Bleomycin*/Bleomycin*/adverse effects

• Source: Scientific reports [Sci Rep] 2025 Aug 04; Vol. 15 (1), pp. 28339. Date of Electronic Publication: 2025 Aug 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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