نتائج البحث

C-176 reduces inflammation-induced pain by blocking the cGAS-STING pathway in microglia.

• Authors : Yang SM; College of Life Science, Northwest University, Xi'an, China.; Department of Anatomy, Histology and Embryology and K.K. Leung Brain Research Centre, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.

Subjects: Microglia*/Microglia*/Microglia*/drug effects ; Microglia*/Microglia*/Microglia*/metabolism ; Nucleotidyltransferases*/Nucleotidyltransferases*/Nucleotidyltransferases*/metabolism

• Source: The International journal of neuroscience [Int J Neurosci] 2025 Nov; Vol. 135 (11), pp. 1193-1207. Date of Electronic Publication: 2024 May 13.Publisher: Informa Healthcare Country of Publication: England NLM ID: 0270707 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Maresin 2, a Specialized Pro-Resolution Lipid Mediator, Reduces Pain and Inflammation Induced by Bothrops jararaca Venom in Mice.

• Authors : Dantas KLS; Laboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Immunology, Parasitology and General Pathology, Londrina State University, Londrina 86057-970, PR, Brazil.; Bianchini BHS

Subjects: Docosahexaenoic Acids*/Docosahexaenoic Acids*/Docosahexaenoic Acids*/therapeutic use ; Docosahexaenoic Acids*/Docosahexaenoic Acids*/Docosahexaenoic Acids*/pharmacology ; Inflammation*/Inflammation*/Inflammation*/drug therapy

• Source: Toxins [Toxins (Basel)] 2025 Jul 25; Vol. 17 (8). Date of Electronic Publication: 2025 Jul 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651

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iNOS Mediates High-Fat Diet-Associated Aggravation of Complete Freund's Adjuvant-Induced Inflammatory Pain.

• Authors : Lee EW; Department of Anaesthesiology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Wang L

Subjects: Diet, High-Fat*/Diet, High-Fat*/Diet, High-Fat*/adverse effects ; Freund's Adjuvant*/Freund's Adjuvant*/Freund's Adjuvant*/adverse effects ; Nitric Oxide Synthase Type II*/Nitric Oxide Synthase Type II*/Nitric Oxide Synthase Type II*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jun 05; Vol. 26 (11). Date of Electronic Publication: 2025 Jun 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Demyelination-related pain: role of lysophosphatidic acid in satellite glial cell-neuron crosstalk.

• Authors : Wang Y; Department of Physiology, School of Basic Medical Sciences, Harbin Medical University, Harbin, Heilongjiang, 150081, China.; Heilongjiang Provincial key Laboratory of Precise Diagnosis and Neuropsychological Regulation of Mental Disorders, Qiqihar Medical University, Qiqihar, Heilongjiang, 161006, China.

Subjects: Lysophospholipids*/Lysophospholipids*/Lysophospholipids*/metabolism ; Neuroglia*/Neuroglia*/Neuroglia*/metabolism ; Neuroglia*/Neuroglia*/Neuroglia*/pathology

• Source: Journal of translational medicine [J Transl Med] 2025 Dec 13; Vol. 23 (1), pp. 1425. Date of Electronic Publication: 2025 Dec 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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Ginkgo biloba attenuates complete Freund's adjuvant-induced inflammatory pain by suppressing the NF-κB-CXCL1/CXCR2 signaling cascade in the rat spinal cord.

• Authors : Salam SA; Department of Biological Sciences, Faculty of Science, King Faisal University, Al-Ahsa, Saudi Arabia.; Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt.

Subjects: Ginkgo biloba*/Ginkgo biloba*/Ginkgo biloba*/chemistry ; NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; Inflammation*/Inflammation*/Inflammation*/drug therapy

• Source: Redox report : communications in free radical research [Redox Rep] 2025 Dec; Vol. 30 (1), pp. 2447778. Date of Electronic Publication: 2024 Dec 31.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9511366 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Combined Systemic and Cutaneous Ovalbumin–Aluminum Sensitization Triggers Thermal Hyperalgesia, Spinal Gliosis, and Nociceptive Nerve Fibers Sprouting in Mice.

• Authors : Siquier-Dameto, Gabriel^1,2 (AUTHOR); Gimeno-Beltrán, Javier^2,3 (AUTHOR); Bellia, Gilberto^3,4 (AUTHOR)

• Source: Physiologia. Sep2025, Vol. 5 Issue 3, p32. 30p.

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Red induces hyperalgesia and white induces hypoalgesia regardless of pain modality.

• Authors : Wiercioch-Kuzianik K; Pain Research Group, Institute of Psychology, Jagiellonian University, ul. Ingardena 6, 30-060, Kraków, Poland. .; Brączyk J

Subjects: Hyperalgesia* ; Pain*; Humans

• Source: Scientific reports [Sci Rep] 2023 Apr 19; Vol. 13 (1), pp. 6360. Date of Electronic Publication: 2023 Apr 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Neuronal Endothelin a Receptor Mediates Experimental and Clinical Vascular Pain through an Endothelial-Neural Axis.

• Authors : Jiang ZJ; School of Pharmacy, Nantong University, Nantong, Jiangsu Province, 226019, China.; Pain and Related Disease Research Laboratory, Shantou University Medical College, Shantou, Guangdong Province, 515041, China.

Subjects: Receptor, Endothelin A*/Receptor, Endothelin A*/Receptor, Endothelin A*/metabolism ; Receptor, Endothelin A*/Receptor, Endothelin A*/Receptor, Endothelin A*/genetics ; Endothelial Cells*/Endothelial Cells*/Endothelial Cells*/metabolism

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Nov; Vol. 12 (42), pp. e12375. Date of Electronic Publication: 2025 Aug 14.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Mechanical Acupuncture at ST36 Attenuates Inflammatory Pain Involving TRPV1 Signaling in Mice.

• Authors : Kang SY; Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.; Bang SK

Subjects: TRPV Cation Channels*/TRPV Cation Channels*/TRPV Cation Channels*/metabolism ; Inflammation*/Inflammation*/Inflammation*/therapy ; Inflammation*/Inflammation*/Inflammation*/metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 02; Vol. 26 (17). Date of Electronic Publication: 2025 Sep 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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FK506 causes pain by upregulating NaV1.7 channels in the spinal dorsal root ganglia of NaV1.7-ChR2 mice.

• Authors : Maruta T; Department of Anesthesiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.; Department of Anesthesiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Subjects: Ganglia, Spinal*/Ganglia, Spinal*/Ganglia, Spinal*/metabolism ; Ganglia, Spinal*/Ganglia, Spinal*/Ganglia, Spinal*/drug effects ; Tacrolimus*/Tacrolimus*/Tacrolimus*/adverse effects

• Source: Molecular pain [Mol Pain] 2026 Jan-Dec; Vol. 22, pp. 17448069251414260. Date of Electronic Publication: 2026 Jan 03.Publisher: Sage Publications Inc Country of Publication: United States NLM ID: 101242662 Publication Model: Print-Electronic Cited Medium: Internet

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