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Academic Journal

Cerebrospinal Fluid Amyloid and Tau Biomarker Changes Across the Alzheimer Disease Clinical Spectrum

Subjects: Humans; Alzheimer Disease/cerebrospinal fluid diagnosis; tau Proteins/cerebrospinal fluid

  • Source: de Leeuw, D M, Trieu, C, Vromen, E M, Blujdea, E R, Verberk, I M W, Duits, F H, Teunissen, C E, Pijnenburg, Y A L, van der Flier, W M, van Harten, A C, Visser, P J & Tijms, B M 2025, '

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Academic Journal

Cerebrospinal fluid proteome alterations related to depressive symptoms in cognitive decline and Alzheimer's disease

Subjects: Alzheimer's disease; amyloid pathology; cerebrospinal fluid

  • Source: Rabl, M, Hartog, W L, van der Flier, W M, Pijnenburg, Y A L, Teunissen, C E, Tsolaki, M, Freund-Levi, Y, Vandenberghe, R, Froelich, L, Streffer, J, Lovestone, S, Bertram, L, Zetterberg, H, Gobom, J,

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Academic Journal

Cerebrospinal fluid proteomic associations of APOE genotypes reveal distinct protective and risk mechanisms for Alzheimer's disease

Subjects: Alzheimer's disease; apolipoprotein E; cerebrospinal fluid

  • Source: Vromen, E M, Lageman, S B, Gobom, J, van der Kant, R, Dobricic, V, Bertram, L, Streffer, J, Lovestone, S, Vos, S J B, Tainta, M, Freund-Levi, Y, Frolich, L, Popp, J, Peyratout, G, Tsolaki, M, Verhey,

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Academic Journal

Integrative analysis of cerebrospinal fluid biomarkers, metabolomics, and polygenic risk reveals novel metabolite associations with Alzheimer's disease

Subjects: Alzheimer's disease; amyloid-beta; biomarkers

  • Source: Francia, M, Ramesh, N, Boltz, T, Bot, M, van der Flier, W M, Visser, P J, van der Lee, S, Teunissen, C E, Pijnenburg, Y A L, den Braber, A, Loohuis, L O, Reus, L M, Tijms, B M & Ophoff, R A 2025,

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Academic Journal

Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer's disease

Subjects: Inflammation; Biomarkers; Cerebrospinal fluid

  • Source: Nordengen, K, Kirsebom, B-E, Richter, G, Palhaugen, L, Gisladottir, B, Siafarikas, N, Nakling, A, Rongve, A, Brathen, G, Grontvedt, G R, Gonzalez, F, Waterloo, K, Sharma, K, Karikari, T, Vromen, E M,

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Academic Journal

Sphingolipids in Cerebrospinal Fluid and Plasma Lipoproteins of APOE4 Homozygotes and Non-APOE4 Carriers with Mild Cognitive Impairment versus Subjective Cognitive Decline

Subjects: Alzheimer's disease; amyloid-beta peptides; Apolipoprotein E4

  • Source: den Hoedt, S, Dorst-Lagerwerf, K Y, de Vries, H E, Rozemuller, A J M, Scheltens, P, Walter, J, Sijbrands, E J G, Martinez-Martinez, P, Verhoeven, A J M, Teunissen, C E & Mulder, M T 2023,

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Academic Journal

Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology

Subjects: Alzheimer's disease; biomarkers; cerebrospinal fluid

  • Source: Delvenne, A, Gobom, J, Tijms, B, Bos, I, Reus, L M, Dobricic, V, Ten Kate, M, Verhey, F, Ramakers, I, Scheltens, P, Teunissen, C E, Vandenberghe, R, Schaeverbeke, J, Gabel, S, Popp, J, Peyratout, G,

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Academic Journal

Cerebrospinal fluid proteomic profiling of cognitively unimpaired individuals with suspected non-Alzheimer's disease pathophysiology

Subjects: biomarkers; cognitively unimpaired; proteomics

  • Source: Delvenne, A, Gobom, J, Reus, L M, Dobricic, V, Ten Kate, M, Schindler, S E, Ramakers, I, Tijms, B M, Vandenberghe, R, Schaeverbeke, J, Martinez-Lage, P, Tainta, M, Teunissen, C E, Popp, J, Peyratout,

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