بيانات النشر: Umeå universitet, Institutionen för psykologi
Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Finnish Institute of Occupational Health, Helsinki, Finland
UCL Brain Sciences, University College London, London, United Kingdom
Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Finnish Institute of Occupational Health, Helsinki, Finland; Department of Public Health, University of Turku and Turku University Hospital, Turku, Finland; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Centre for Occupational and Environmental Medicine, Stockholm County Council, Sweden
Finnish Institute of Occupational Health, Helsinki, Finland
Population-based Cohorts Unit, Université Paris Cité, Paris, France; UVSQ, UMS 011 Inserm, Paris Saclay University, Paris, France
Department of Health Sciences, Mid Sweden University, Sundsvall, Sweden
Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland
Stress Research Institute, University of Stockholm, Stockholm, Sweden
Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Helsinki University Hospital, Helsinki, Finland
Department of Public Health, University of Turku and the Wellbeing Services County of Southwest Finland, Research Unit, Turku, Finland; School of Health Science, University of Skövde, Skövde, Sweden
Department of Public Health, University of Turku and Turku University Hospital, Turku, Finland; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; School of Educational Sciences and Psychology, University of Eastern Finland, Joensuu, Finland
Department of Public Health, University of Turku and Turku University Hospital, Turku, Finland; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland; Research Services, University of Turku and Turku University Hospital, Turku, Finland
UCL Brain Sciences, University College London, London, United Kingdom; Epidemiology of Ageing and Neurodegenerative Diseases, U1153 Inserm, Université Paris Cité, Paris, France
Division of Surgery & Interventional Science, Faculty of Medical Sciences, University College London, London, United Kingdom
Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Finnish Institute of Occupational Health, Helsinki, Finland; UCL Brain Sciences, University College London, London, United Kingdom
نبذة مختصرة : Background: Regular physical activity is recommended for all aged 5 years and older, but the health benefits gained might differ across population subgroups. The aim of this study was to examine these benefits in terms of years lived free from major non-communicable diseases in subgroups with varying levels of risk factors. Methods: Our analysis was based on a multicohort study of initially healthy European adults from the IPD-Work Consortium and initially healthy participants from the UK Biobank study. Self-reported leisure-time physical activity levels at baseline (1986–2010) were categorised as low (no or very little), intermediate (between low and recommended levels), and WHO-recommended (≥2·5 h of moderate or ≥1·25 h of vigorous physical activity per week). We divided the study population into 36 overlapping subgroups based on socioeconomic factors, lifestyle, and mental health at baseline, and assessed disease-free years between ages 40 years and 75 years for both the overall population and subgroups, accounting for coronary heart disease, stroke, type 2 diabetes, cancer, asthma, and chronic obstructive pulmonary disease. Findings: 14 IPD-Work studies were assessed and six studies were excluded due to missing outcome data and unavailable data for pooling, resulting in the inclusion of eight studies with 124 909 participants. After the exclusion of 7685 participants due to prevalent diseases and 9265 due to missing data, the sample consisted of 107 959 initially healthy European adults (63 567 [58·9%] females and 44 392 [41·1%] males) from the IPD-Work consortium. For the UK Biobank sample, 9 238 453 million individuals were invited, 8 736 094 (94·6%) were non-respondents, and 502 359 participated in the baseline examination. After the exclusion of 73 460 participants, 428 899 participants had data on at least one measure of physical activity. 236 258 (55·1%) were female and 192 641 (44·9%) were male. During 1·6 million person-years at risk, 21 231 IPD-Work participants developed a non-communicable disease, ...
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