A de novo TLR7 gain-of-function mutation causing severe monogenic lupus in an infant

Stremenova Spegarova, J, Sinnappurajar, P, Al Julandani, D, Navickas, R, Griffin, H, Ahuja, M, Grainger, A, Livingstone, K, Rice, G I, Sutherland, F, Hayes, C, Parke, S, Pang, L, Roderick, M R, Slatter, M, Crow, Y, Ramanan, A V & Hambleton, S 2024, 'A de novo TLR7 gain-of-function mutation causing severe monogenic lupus in an infant', The Journal of clinical investigation, vol. 134, no. 13, e179193. https://doi.org/10.1172/JCI179193

Humans; Lupus Erythematosus; Systemic/genetics; Toll-Like Receptor 7/genetics; Infant; Gain of Function Mutation; Female; Male

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