نبذة مختصرة : Background: Obesity (body mass index [BMI] ≥30 kg/m2) is associated with a range of physical and psychiatric comorbidities and premature mortality. Young adulthood (here 16-25 years) constitutes a vulnerable period for weight gain, poor weight loss results, and mental health problems. Up to 8.3% of Swedish young adults are classified as obese. In spite of the fact that the peak incidence for obesity occurs during young adulthood, this age period has been generally overlooked in clinical obesity research, particularly in regard to obesity-related mental health problems. Aim: To characterize severe obesity (BMI ≥35 kg/m2) in young adulthood (16-25 years) with emphasis on mental health aspects, and to study long-term outcomes (weight loss, adverse events, loss-to-follow-up and health-related quality of life [HRQL]) in young (18-25 years) vs older (≥26 years) adults after Roux-en-Y gastric bypass (RYGB). Methods: In Study I, we used cross-sectional self-reported questionnaire data on obesity-related comorbidities, mental health, self-esteem, lifestyle and health-related quality of life; physical fitness tests; biochemical data on micronutritional deficiencies; and anthropometry from n=165 young adults, aged 16-25 years who were about to start treatment at the Karolinska University Hospital Obesity Center. In Study II, we compared cross-sectional questionnaire patient data (n=121 treatment-seekers to the Obesity Center, 18-25 years) on mental distress, self-reported suicide attempts, physical/psychosomatic symptoms, and quality of life with data on n=363 normal-weight responders to the Stockholm Public Health Cohort 2010 who were individually matched 3:1 for age, gender and socioeconomic status. For Studies III-IV, we frequency matched n=3,531 young (18-25 years) to n=17,137 older (26-74 years) patients in the Scandinavian Obesity Surgery Registry for BMI, gender and year of surgery to compare weight loss, adverse events, loss-to-follow-up and changes in HRQL between matching groups. Results: In Study I, we found ...
Relation: I. Dreber H, Reynisdottir S, Angelin B, Hemmingsson E. Who is the treatment-seeking young adult with severe obesity? – A comprehensive characterization with emphasis on mental health. PLoS One. 2015 Dec 22;10(12):e0145273. ::doi::10.1371/journal.pone.0145273 ::pmid::26694031 ::isi::000367092500034; II. Dreber H, Reynisdottir S, Angelin B, Tynelius F, Rasmussen F, Hemmingsson E. Mental distress in treatment-seeking young adults (18-25 years) with severe obesity compared with population controls of different body mass index levels: cohort study. Clin Obes. 2017 Feb;7(1):1-10. ::doi::10.1111/cob.12170 ::pmid::28058812 ::isi::000396992400001; III. Dreber H, Thorell A, Torgerson J, Reynisdottir S, Hemmingsson E. Weight loss, adverse events and loss-to-follow-up 5 years after Roux-en-Y gastric bypass in young (18-25 y) versus older (≥26 y) adults: a Scandinavian Obesity Surgery Registry Study. [Submitted]; IV. Dreber H, Thorell A, Reynisdottir S, Hemmingsson E. Health-related quality of life 5 years after Roux-en-Y gastric bypass in young (18-25 y) versus older (≥26 y) adults: a Scandinavian Obesity Surgery Registry Study. [Submitted]; http://hdl.handle.net/10616/46284
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