An Imidazo-Pyridin-Derived Fluorescent Probe for Monitoring Hydrogen Sulfide in Chinese Medicinal Materials.

Publisher: Springer- Country of Publication: Netherlands NLM ID: 9201341 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4994 (Electronic) Linking ISSN: 10530509 NLM ISO Abbreviation: J Fluoresc Subsets: MEDLINE

Publication: Amsterdam : Springer-
Original Publication: New York : Plenum Press, c1991-

Hydrogen Sulfide*/analysis ; Fluorescent Dyes*/chemistry ; Fluorescent Dyes*/chemical synthesis ; Pyridines*/chemistry ; Imidazoles*/chemistry ; Drugs, Chinese Herbal*/chemistry ; Drugs, Chinese Herbal*/analysis; Spectrometry, Fluorescence ; Humans ; Molecular Structure

Herein, an imidazo-pyridin-derived fluorescent probe ImPy-HS was developed for monitoring the hydrogen sulfide (H2S) level in the water decoction of Chinese medicinal materials. Under the excitation at 355 nm, ImPy-HS exhibited the obvious fluorescence response at 490 nm. The detection system with ImPy-HS showed the advantages including relatively high sensitivity, high selectivity, and high steadiness. Especially, in the water decoction of Chinese medicinal materials with H2S from both addition and excessive fumigation then reduction, ImPy-HS achieved the monitoring of the H2S level. ImPy-HS also realized the imaging of both exogenous and endogenous H2S as well as the water decoction-treated affection. The information here was meaningful for studying the quality control of Chinese medicinal materials.
(© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Declarations. Competing Interests: The authors declare no competing interests.

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Keywords: Chinese medicinal materials; Fluorescent probe; Hydrogen sulfide; Imidazo-pyridin moiety

YY9FVM7NSN (Hydrogen Sulfide)
0 (Fluorescent Dyes)
0 (Pyridines)
0 (Imidazoles)
0 (Drugs, Chinese Herbal)

Date Created: 20250204 Date Completed: 20251104 Latest Revision: 20251104

20260130

10.1007/s10895-024-04083-z

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