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Editorial & Opinion

Bidirectional crosstalk between cancer cells and cancer-associated fibroblasts in mixed organoid system elicits transcriptomic characteristics of pancreatic cancer with potential therapeutic vulnerabilities.

  • Authors : Choi JI; Department of Pathology, Ajou University School of Medicine, Suwon, South Korea.; Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, South Korea.

Subjects: Cancer-Associated Fibroblasts* ; Pancreatic Neoplasms*/Pancreatic Neoplasms*/Pancreatic Neoplasms*/genetics; Humans

  • Source: Clinical and translational medicine [Clin Transl Med] 2024 Feb; Vol. 14 (2), pp. e1597.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

The molecular classification of cancer-associated fibroblasts on a pan-cancer single-cell transcriptional atlas.

  • Authors : Chen B; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Sir Y.K. Pao Cancer Center, The Chinese University of Hong Kong, Hong Kong, China.; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong, China.

Subjects: Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/metabolism ; Neoplasms*/Neoplasms*/Neoplasms*/pathology; Humans

  • Source: Clinical and translational medicine [Clin Transl Med] 2023 Dec; Vol. 13 (12), pp. e1516.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

H. pylori-induced NF-κB-PIEZO1-YAP1-CTGF axis drives gastric cancer progression and cancer-associated fibroblast-mediated tumour microenvironment remodelling.

  • Authors : Chen B; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Sir Y.K. Pao Cancer Center, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.; Institute of Digestive Disease, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong, China.

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology ; Helicobacter pylori*/Helicobacter pylori*/Helicobacter pylori*/metabolism ; Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/metabolism

  • Source: Clinical and translational medicine [Clin Transl Med] 2023 Nov; Vol. 13 (11), pp. e1481.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

Single-cell and spatial transcriptomics reveal POSTN + cancer-associated fibroblasts correlated with immune suppression and tumour progression in non-small cell lung cancer.

  • Authors : Chen C; Department of Thoracic Surgery, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen, China.; Guo Q

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/metabolism ; Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/Cancer-Associated Fibroblasts*/metabolism ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/metabolism

  • Source: Clinical and translational medicine [Clin Transl Med] 2023 Dec; Vol. 13 (12), pp. e1515.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

Is the practice of colorectal cancer screening questionable after the NordICC trial was published?

  • Authors : Wong MCS; Centre for Health Education and Health Promotion, JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Huang J

Subjects: Early Detection of Cancer* ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/diagnosis ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/prevention & control

  • Source: Clinical and translational medicine [Clin Transl Med] 2023 Oct; Vol. 13 (10), pp. e1365.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Report

Hypoxic microenvironment determines the phenotypic plasticity and spatial distribution of cancer-associated fibroblasts.

  • Authors : Choi JI; Department of Pathology, Ajou University School of Medicine, Suwon, South Korea.; Department of Biomedical Sciences, Ajou University Graduate School of Medicine, Suwon, South Korea.

Subjects: Cancer-Associated Fibroblasts* ; Neoplasms*/Neoplasms*/Neoplasms*/genetics; Humans

  • Source: Clinical and translational medicine [Clin Transl Med] 2023 Oct; Vol. 13 (10), pp. e1438.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

mRNA vaccine in cancer therapy: Current advance and future outlook.

  • Authors : Li Y; Department of Breast Surgery, Baoji Municipal Central Hospital, Weibin District, Baoji, Shaanxi, China.; Wang M

Subjects: Cancer Vaccines*/Cancer Vaccines*/Cancer Vaccines*/genetics ; Cancer Vaccines*/Cancer Vaccines*/Cancer Vaccines*/therapeutic use ; COVID-19*/COVID-19*/COVID-19*/prevention & control

  • Source: Clinical and translational medicine [Clin Transl Med] 2023 Aug; Vol. 13 (8), pp. e1384.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

Integrated single-cell and spatial transcriptomic profiling reveals higher intratumour heterogeneity and epithelial-fibroblast interactions in recurrent bladder cancer.

  • Authors : Shi ZD; Department of Urology, Xuzhou Clinical School of Xuzhou Medical University, Xuzhou Central Hospital, Xuzhou, Jiangsu, China.; School of Life Sciences, Jiangsu Normal University, Jiangsu, China.

Subjects: Urinary Bladder Neoplasms* ; Cancer-Associated Fibroblasts*; Humans

  • Source: Clinical and translational medicine [Clin Transl Med] 2023 Jul; Vol. 13 (7), pp. e1338.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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Academic Journal

Tumor vaccine based on extracellular vesicles derived from γδ-T cells exerts dual antitumor activities.

  • Authors : Wang X; Department of Paediatrics & Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.; Zhang Y

Subjects: Cancer Vaccines* ; Extracellular Vesicles*; Adjuvants, Immunologic

  • Source: Journal of extracellular vesicles [J Extracell Vesicles] 2023 Sep; Vol. 12 (9), pp. e12360.Publisher: Wiley Country of Publication: United States NLM ID: 101610479 Publication Model: Print Cited Medium: Internet

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Report

A peek at the other side of the coin: Tumor-suppressor role of microRNAs expressed by pancreatic cancer-associated fibroblasts.

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; Cancer-Associated Fibroblasts* ; Neoplasms*

  • Source: Clinical and translational medicine [Clin Transl Med] 2023 Aug; Vol. 13 (8), pp. e1357.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet

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