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Academic Journal

Datura stramonium Flowers as a Potential Natural Resource of Bioactive Molecules: Identification of Anti-Inflammatory Agents and Molecular Docking Analysis.

Authors : Damergi B; Laboratory of Bioactive Substances, Biotechnology Center of Borj Cedria, BP-901, Hammam-Lif 2050, Tunisia.; Faculty of Sciences of Tunis, University of Tunis El Manar, Tunis 2092, Tunisia.

Subjects: Datura stramonium*; Molecular Docking Simulation ; Plant Extracts/Plant Extracts/Plant Extracts/chemistry

Source: Molecules (Basel, Switzerland) [Molecules] 2023 Jul 04; Vol. 28 (13). Date of Electronic Publication: 2023 Jul 04.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Identification of Novel Cyclooxygenase-1 Selective Inhibitors of Thiadiazole-Based Scaffold as Potent Anti-Inflammatory Agents with Safety Gastric and Cytotoxic Profile.

Authors : Haroun M; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.; Fesatidou M

Subjects: Thiadiazoles*/Thiadiazoles*/Thiadiazoles*/therapeutic use ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology; Humans

Source: Molecules (Basel, Switzerland) [Molecules] 2023 Apr 12; Vol. 28 (8). Date of Electronic Publication: 2023 Apr 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Drug Design, Synthesis and Biological Evaluation of Heterocyclic Molecules as Anti-Inflammatory Agents.

Authors : Savjani J; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, S.G.Highway, Ahmedabad 382481, India.; Variya B

Subjects: Chemistry Techniques, Synthetic* ; Drug Design*; Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/Anti-Inflammatory Agents, Non-Steroidal/*chemistry

Source: Molecules (Basel, Switzerland) [Molecules] 2022 Feb 14; Vol. 27 (4). Date of Electronic Publication: 2022 Feb 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Synthesis, In Vitro Anti-Inflammatory Activity, and HRMS Analysis of New Amphetamine Derivatives.

Authors : Manolov S; Department of Organic Chemistry, Faculty of Chemistry, University of Plovdiv, 4000 Plovdiv, Bulgaria.; Ivanov I

Subjects: Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/chemistry ; Ketoprofen*/Ketoprofen*/Ketoprofen*/chemistry

Source: Molecules (Basel, Switzerland) [Molecules] 2022 Dec 24; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Discovery of 5-Methylthiazole-Thiazolidinone Conjugates as Potential Anti-Inflammatory Agents: Molecular Target Identification and In Silico Studies.

Authors : Haroun M; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.; Petrou A

Subjects: Lipoxygenase Inhibitors*/Lipoxygenase Inhibitors*/Lipoxygenase Inhibitors*/pharmacology ; Cyclooxygenase Inhibitors*/Cyclooxygenase Inhibitors*/Cyclooxygenase Inhibitors*/pharmacology ; Cyclooxygenase Inhibitors*/Cyclooxygenase Inhibitors*/Cyclooxygenase Inhibitors*/chemistry

Source: Molecules (Basel, Switzerland) [Molecules] 2022 Nov 22; Vol. 27 (23). Date of Electronic Publication: 2022 Nov 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Pyrazoles and Pyrazolines as Anti-Inflammatory Agents.

Authors : Mantzanidou M; Department of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.; Pontiki E

Subjects: Anti-Inflammatory Agents/Anti-Inflammatory Agents/Anti-Inflammatory Agents/*chemical synthesis ; Lipoxygenase/Lipoxygenase/Lipoxygenase/*chemistry ; Lipoxygenase Inhibitors/Lipoxygenase Inhibitors/Lipoxygenase Inhibitors/*chemical synthesis

Source: Molecules (Basel, Switzerland) [Molecules] 2021 Jun 05; Vol. 26 (11). Date of Electronic Publication: 2021 Jun 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Solubility Optimization of Loxoprofen as a Nonsteroidal Anti-Inflammatory Drug: Statistical Modeling and Optimization.

Authors : Alqarni M; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, Taif 21944, Saudi Arabia.; Namazi NI

Subjects: Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/pharmacology ; Artificial Intelligence*; Anti-Inflammatory Agents

Source: Molecules (Basel, Switzerland) [Molecules] 2022 Jul 07; Vol. 27 (14). Date of Electronic Publication: 2022 Jul 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Synthesis of Tricyclic Pterolobirin H Analogue: Evaluation of Anticancer and Anti-Inflammatory Activities and Molecular Docking Investigations.

Authors : Zentar H; Departamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, 18071 Granada, Spain.; Departamento de Bioquímica y Biología Molecular I, Facultad de Ciencias, Universidad de Granada, 18071 Granada, Spain.

Subjects: Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/Anti-Inflammatory Agents*/pharmacology ; Liver Neoplasms*; Humans

Source: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 23; Vol. 28 (17). Date of Electronic Publication: 2023 Aug 23.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Spin-Labeled Diclofenac: Synthesis and Interaction with Lipid Membranes.

Authors : Baranov DS; Voevodsky Institute of Chemical Kinetics and Combustion, Russian Academy of Sciences, 630090 Novosibirsk, Russia.; Kashnik AS

Subjects: Diclofenac* ; Anti-Inflammatory Agents, Non-Steroidal*; Spin Labels

Source: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 10; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 10.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

Synthesis, Biological, Spectroscopic and Computational Investigations of Novel N -Acylhydrazone Derivatives of Pyrrolo[3,4- d ]pyridazinone as Dual COX/LOX Inhibitors.

Authors : Mikus J; Student Science Club of Medicinal Chemistry, Department of Medicinal Chemistry, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.; Świątek P

Subjects: Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/Anti-Inflammatory Agents, Non-Steroidal*/chemistry ; Cyclooxygenase 2 Inhibitors*/Cyclooxygenase 2 Inhibitors*/Cyclooxygenase 2 Inhibitors*/chemistry; Cyclooxygenase 2/Cyclooxygenase 2/Cyclooxygenase 2/metabolism

Source: Molecules (Basel, Switzerland) [Molecules] 2023 Jul 18; Vol. 28 (14). Date of Electronic Publication: 2023 Jul 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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نتائج البحث

فلترة النتائج

Datura stramonium Flowers as a Potential Natural Resource of Bioactive Molecules: Identification of Anti-Inflammatory Agents and Molecular Docking Analysis.

Identification of Novel Cyclooxygenase-1 Selective Inhibitors of Thiadiazole-Based Scaffold as Potent Anti-Inflammatory Agents with Safety Gastric and Cytotoxic Profile.

Drug Design, Synthesis and Biological Evaluation of Heterocyclic Molecules as Anti-Inflammatory Agents.

Synthesis, In Vitro Anti-Inflammatory Activity, and HRMS Analysis of New Amphetamine Derivatives.

Discovery of 5-Methylthiazole-Thiazolidinone Conjugates as Potential Anti-Inflammatory Agents: Molecular Target Identification and In Silico Studies.

Pyrazoles and Pyrazolines as Anti-Inflammatory Agents.

Solubility Optimization of Loxoprofen as a Nonsteroidal Anti-Inflammatory Drug: Statistical Modeling and Optimization.

Synthesis of Tricyclic Pterolobirin H Analogue: Evaluation of Anticancer and Anti-Inflammatory Activities and Molecular Docking Investigations.

Spin-Labeled Diclofenac: Synthesis and Interaction with Lipid Membranes.

Synthesis, Biological, Spectroscopic and Computational Investigations of Novel N -Acylhydrazone Derivatives of Pyrrolo[3,4- d ]pyridazinone as Dual COX/LOX Inhibitors.