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The Activation of the Fibrodysplasia Ossificans Progressiva-Inducing ALK2-R206H Mutant Depends on the Distinct Homo-Oligomerization Patterns of ACVR2B and ACVR2A

• Authors : Szabina Szófia Szilágyi; Wiktor Burdzinski; Jerome Jatzlau

Subjects: 0301 basic medicine; Activin Receptors, Type II; ALK2

• Source: CellsCells, Vol 13, Iss 3, p 221 (2024)

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Therapeutische Adressierung des PI3K/mTOR-Signalwegs in T-Zell-Lymphomen ; Therapeutic Targeting of the PI3K/mTOR Signaling Pathway in T-Cell Lymphomas

• Authors : Thielking, Lennart Hagen;

Subjects: T-Zell-Lymphome; PI3K/mTOR-Signalweg; Krebstherapie610

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ST-2191, an Anellated Bismorpholino Derivative of Oxy-Fingolimod, Shows Selective S1P1 Agonist and Functional Antagonist Potency In Vitro and In Vivo

• Authors : Bisera Stepanovska Tanturovska; Aleksandra Zivkovic; Faik Imeri

Subjects: 0301 basic medicine; Multiple Sclerosis; ddc:540

• Source: MoleculesMolecules, Vol 26, Iss 17, p 5134 (2021)Volume 26Issue 17Stepanovska Tanturovska, Bisera; Zivkovic, Aleksandra; Imeri, Faik; Homann, Thomas; Kleuser, Burkhard; Stark,

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TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch

• Authors : Holger Stark; Jenny Wilzopolski; Kristine Rossbach

Subjects: Male; 0301 basic medicine; 600 Technik, Medizin, angewandte Wissenschaften::630 Landwirtschaft::630 Landwirtschaft und verwandte Bereiche

• Source: BiomoleculesBiomolecules, Vol 11, Iss 8, p 1166 (2021)Volume 11Issue 8

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Epigenetic DNA Methylation of EBI3 Modulates Human Interleukin-35 Formation via NFkB Signaling: A Promising Therapeutic Option in Ulcerative Colitis

• Authors : Alexandra Wetzel; Bettina Scholtka; Fabian Schumacher

Subjects: 0301 basic medicine; EBI3; Colon

• Source: Int J Mol SciInternational Journal of Molecular SciencesVolume 22Issue 10

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Biased Ligands Differentially Shape the Conformation of the Extracellular Loop Region in 5-HT2B Receptors

• Authors : Katrin Denzinger; Trung Ngoc Nguyen; Theresa Noonan

Subjects: 0301 basic medicine; Serotonin; Protein Conformation

• Source: Int J Mol SciInternational Journal of Molecular SciencesVolume 21Issue 24

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Apoptosis signaling triggered by the marine alkaloid ascididemin is routed via caspase-2 and JNK to mitochondria

• Authors : Angelika M. Vollmar; Verena M. Dirsch; Bert Steffan

Subjects: 0301 basic medicine; Time Factors; Cell Survival

• Source: Oncogene. 23:1586-1593

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Endothelial tip-cell position, filopodia formation and biomechanics require BMPR2 expression and signaling.

• Authors : Hiepen C; Freie Universität Berlin, Institute for Chemistry and Biochemistry, Thielallee 63, 14195, Berlin, Germany. .; Westphalian University of Applied Sciences, August-Schmidt-Ring 10, 45665, Recklinghausen, Germany. .

Subjects: Pseudopodia*/Pseudopodia*/Pseudopodia*/metabolism ; Pseudopodia*/Pseudopodia*/Pseudopodia*/physiology ; Zebrafish*/Zebrafish*/Zebrafish*/genetics

• Source: Communications biology [Commun Biol] 2025 Jan 08; Vol. 8 (1), pp. 21. Date of Electronic Publication: 2025 Jan 08.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Development of non-nucleotide ADPR antagonists for inhibition of TRPM2 ; Entwicklung von niedermolekularen ADPR Antagonisten zur Inhibtion von TRPM2

• Authors : Ohol, Swati Balasaheb;

Subjects: TRP channel; Electrophysiology; Computer-aided drug design (CADD)

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Luminescent and fluorescent triple reporter plasmid constructs for Wnt, Hedgehog and Notch pathway

• Authors : Julia Maier; Salma Elmenofi; Alexander Taschauer

Subjects: 0301 basic medicine; PROTEINS; Science

• Source: PLoS OnePLoS ONE, Vol 14, Iss 12, p e0226570 (2019)

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