نتائج البحث

Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of the antimalarial drug pyronaridine in human whole blood

• Authors : Schouten, Wietse M.; Roseboom, Ignace C.; Lucas, Luc ...

Subjects: Liquid-liquid extraction; Pharmacokinetics; Pyronaridine

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A randomized, double-blind, single-dose, phase 1 study comparing the pharmacokinetics, pharmacodynamics, safety, and immunogenicity of denosumab biosimilar CT‑P41 and reference denosumab in healthy males.

• Authors : Kim, Anhye; Hong, Jang Hee; Shin, Wonsuk

Subjects: Biosimilar; CT‑P41; denosumab

• Source: Expert Opinion on Biological Therapy, 1 - 9 (2024-02-22)

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Targeted and untargeted screening for impurities in losartan tablets marketed in Germany by means of liquid chromatography/high resolution mass spectrometry

• Authors : Backer, Laura; Kinzig, Martina; Sörgel, Fritz

Subjects: Clinical Biochemistry; Spectroscopy; Drug Discovery

• Source: Journal of Pharmaceutical and Biomedical Analysis ; page 116160 ; ISSN 0731-7085

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Understanding the behavior of phenylurazole-tyrosine-click electrochemical reaction using hybrid electroanalytical techniques

• Authors : Temgoua, Ranil C.T.; Dontsi, Fabiola T.; Lebègue, Estelle

Subjects: Clinical Biochemistry; Spectroscopy; Drug Discovery

• Source: Journal of Pharmaceutical and Biomedical Analysis ; volume 245, page 116147 ; ISSN 0731-7085

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SARS-CoV-2 resistance to monoclonal antibodies and small-molecule drugs

• Authors : Iketani, Sho; Ho, David D.; NIAID

Subjects: Clinical Biochemistry; Drug Discovery; Pharmacology

• Source: Cell Chemical Biology ; volume 31, issue 4, page 632-657 ; ISSN 2451-9456

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Identification of a novel histone H2A mono-ubiquitination-inhibiting cell-active small molecule

• Authors : Ni, Siyao; Takada, Yuri; Ando, Takaaki ...

Subjects: Organic Chemistry; Clinical Biochemistry; Drug Discovery

• Source: Bioorganic & Medicinal Chemistry Letters ; volume 105, page 129759 ; ISSN 0960-894X

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Cyano-Hydrol green derivatives: Expanding the 9-cyanopyronin-based resonance Raman vibrational palette

• Authors : Fujioka, Hiroyoshi; Murao, Yuta; Okinaka, Momoko ...

Subjects: Organic Chemistry; Clinical Biochemistry; Drug Discovery

• Source: Bioorganic & Medicinal Chemistry Letters ; page 129757 ; ISSN 0960-894X

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Milligram scale enantioresolution of promethazine and its main metabolites, determination of their absolute configuration and assessment of enantioselective effects on human SY-SY5Y cells

• Authors : Coelho, Maria Miguel; Costa, Inês; de Albuquerque, Ana Carolina Ferreira ...

Subjects: Clinical Biochemistry; Spectroscopy; Drug Discovery

• Source: Journal of Pharmaceutical and Biomedical Analysis ; volume 245, page 116152 ; ISSN 0731-7085

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Expanding the ligand spaces for E3 ligases for the design of protein degraders

• Authors : Shah Zaib Saleem, Rahman; Schwalm, Martin P.; Knapp, Stefan ...

Subjects: Organic Chemistry; Clinical Biochemistry; Drug Discovery

• Source: Bioorganic & Medicinal Chemistry ; volume 105, page 117718 ; ISSN 0968-0896

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A turn for the worse: Aβ β-hairpins in Alzheimer’s disease

• Authors : Ruttenberg, Sarah M.; Nowick, James S.; National Institute on Aging

Subjects: Organic Chemistry; Clinical Biochemistry; Drug Discovery

• Source: Bioorganic & Medicinal Chemistry ; volume 105, page 117715 ; ISSN 0968-0896

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