نتائج البحث

The dual-specificity kinase DYRK1A interacts with the Hepatitis B virus genome and regulates the production of viral RNA.

• Authors : Pastor F; International Center for Research in Infectiology (CIRI), INSERM U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, Lyon, France.; Charles E

Subjects: Dyrk Kinases* ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/genetics

• Source: PloS one [PLoS One] 2024 Oct 15; Vol. 19 (10), pp. e0311655. Date of Electronic Publication: 2024 Oct 15 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Differential regulation of expression of the protein kinases DYRK1A and DYRK1B in cancer cells.

• Authors : Vorwerk VA; Institute of Pharmacology and Toxicology, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.; Wilms G

Subjects: Dyrk Kinases* ; Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/metabolism ; Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/Protein-Tyrosine Kinases*/genetics

• Source: Scientific reports [Sci Rep] 2024 Oct 13; Vol. 14 (1), pp. 23926. Date of Electronic Publication: 2024 Oct 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Nuclear F-actin assembly on damaged chromatin is regulated by DYRK1A and Spir1 phosphorylation.

• Authors : Li J; School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, S.A.R.; State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, S.A.R.

Subjects: Actins*/Actins*/Actins*/metabolism ; Cell Nucleus*/Cell Nucleus*/Cell Nucleus*/metabolism ; Chromatin*/Chromatin*/Chromatin*/metabolism

• Source: Nucleic acids research [Nucleic Acids Res] 2024 Aug 27; Vol. 52 (15), pp. 8897-8912.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Functional characterization of two DYRK1B variants causative of AOMS3.

• Authors : Detro-Dassen S; Institute of Pharmacology and Toxicology, RWTH Aachen University, Aachen, Germany.; Sternberg A

Subjects: Dyrk Kinases* ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/genetics ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism

• Source: Orphanet journal of rare diseases [Orphanet J Rare Dis] 2024 Jun 12; Vol. 19 (1), pp. 233. Date of Electronic Publication: 2024 Jun 12.Publisher: BioMed Central Country of Publication: England NLM ID: 101266602 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1172

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Truncated Dyrk1A aggravates neuronal apoptosis by inhibiting ASF-mediated Bcl-x exon 2b inclusion.

• Authors : Zhang S; College of Life Sciences, Henan Normal University, Xinxiang, China.; Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, China.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/genetics ; Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/Protein Serine-Threonine Kinases*/metabolism ; Dyrk Kinases*/Dyrk Kinases*/Dyrk Kinases*/genetics

• Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Apr; Vol. 30 (4), pp. e14493. Date of Electronic Publication: 2023 Oct 21.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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N -Benzylated 5-Hydroxybenzothiophene-2-carboxamides as Multi-Targeted Clk/Dyrk Inhibitors and Potential Anticancer Agents.

• Authors : Mostafa N; Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo 11835, Egypt.; Department of Pharmaceutical Chemistry, School of Pharmacy, Newgiza University, Cairo 12256, Egypt.

• Source: Cancers [Cancers (Basel)] 2024 May 27; Vol. 16 (11). Date of Electronic Publication: 2024 May 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print)

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Loss of the DYRK1A Protein Kinase Results in the Reduction in Ribosomal Protein Gene Expression, Ribosome Mass and Reduced Translation.

• Authors : Di Vona C; Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Dr Aiguader 88, 08003 Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER), 28029 Madrid, Spain.

Subjects: Ribosomal Proteins*/Ribosomal Proteins*/Ribosomal Proteins*/genetics ; Dyrk Kinases*/Dyrk Kinases*/Dyrk Kinases*/genetics ; Dyrk Kinases*/Dyrk Kinases*/Dyrk Kinases*/metabolism

• Source: Biomolecules [Biomolecules] 2023 Dec 25; Vol. 14 (1). Date of Electronic Publication: 2023 Dec 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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The Nitro Group Reshapes the Effects of Pyrido[3,4- g ]quinazoline Derivatives on DYRK/CLK Activity and RNA Splicing in Glioblastoma Cells.

• Authors : Borisevich SS; Ufa Institute of Chemistry, Ufa Federal Research Center of the Russian Academy of Sciences, Ufa 450054, Russia.; Institute of Cyber Intelligence Systems, National Research Nuclear University MEPhI, Moscow 115409, Russia.

• Source: Cancers [Cancers (Basel)] 2024 Feb 19; Vol. 16 (4). Date of Electronic Publication: 2024 Feb 19.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print)

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Regulation of Drosophila brain development and organ growth by the Minibrain/Rala signaling network.

• Authors : Brown M; Department of Biology, University of Massachusetts Boston, Boston, MA 02125, USA.; Sciascia E

Subjects: Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/metabolism ; Drosophila Proteins*/Drosophila Proteins*/Drosophila Proteins*/genetics ; Brain*/Brain*/Brain*/metabolism

• Source: G3 (Bethesda, Md.) [G3 (Bethesda)] 2024 Nov 06; Vol. 14 (11).Publisher: Oxford University Press Country of Publication: England NLM ID: 101566598 Publication Model: Print Cited Medium: Internet ISSN:

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Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A.

• Authors : Widowati EW; Institute of Pharmacology and Toxicology, RWTH Aachen University, Aachen, Germany.; Chemistry Study Program, Faculty of Science and Technology, State Islamic University (UIN) Sunan Kalijaga, Yogyakarta, Indonesia.

Subjects: Mutation/Mutation/Mutation/*genetics ; Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/Protein Serine-Threonine Kinases/*genetics ; Protein-Tyrosine Kinases/Protein-Tyrosine Kinases/Protein-Tyrosine Kinases/*genetics

• Source: BMC research notes [BMC Res Notes] 2018 May 15; Vol. 11 (1), pp. 297. Date of Electronic Publication: 2018 May 15.Publisher: Biomed Central Country of Publication: England NLM ID: 101462768 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-0500

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