Association between pentraxin 3 and growth differentiation factor-15 in adolescent male swimmers

WOS: 000405064300008 ; PubMed: 28664745 ; BACKGROUND: The purpose of this study was to evaluate plasma pentraxin 3 (PTX3) and growth differentiation factor-15 (GDF-15) concentrations in adolescent male swimmers and compare any possible interactions with canonical biochemical parameters. METHODS: Twenty-six adolescent male swimmers and 29 gender- and age-matched sedentary controls participated in this study. Fasting blood samples were taken from the participants. Biochemical values and plasma PTX3 and GDF-15 levels were measured. RESULTS: Plasma PTX-3 levels were markedly higher in the adolescent male swimmers than in the sedentary controls (378.44 +/- 173.93 vs 257.82 +/- 103.20 pg mL(-1), p = 0.002). There was no significant difference in GDF-15 levels between the two groups (186.12 +/- 40.65 vs 203.60 +/- 36.77 pg mL(-1) in the swimmers and the sedentary, respectively, P = 0.068). Relationship between PTX3 and GDF-15 was linear. CONCLUSIONS: This is the first study showing that adolescent male swimmers have higher PTX3 levels than sedentary controls and that there is a linear relationship between PTX3 and GDF-15 (Tab. 3, Fig. 2, Ref 26). Text in PDF www.elis.sk. ; Selcuk University Scientific Research and Project Coordinatorship [13202031] ; This work was supported by the Selcuk University Scientific Research and Project Coordinatorship (project number: 13202031).