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Neural activations to loss anticipation mediates the association between difficulties in emotion regulation and screen media activities among early adolescent youth: A moderating role for depression.

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  • معلومة اضافية
    • المصدر:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101541838 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-9307 (Electronic) Linking ISSN: 18789293 NLM ISO Abbreviation: Dev Cogn Neurosci Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Amsterdam : Elsevier
    • الموضوع:
    • نبذة مختصرة :
      Background: Screen media activities (SMAs; e.g., watching videos, playing videogames) have become increasingly prevalent among youth as ways to alleviate or escape from negative emotional states. However, neural mechanisms underlying these processes in youth are incompletely understood.
      Method: Seventy-nine youth aged 11-15 years completed a monetary incentive delay task during fMRI scanning. Neural correlates of reward/loss processing and their associations with SMAs were explored. Next, brain activations during reward/loss processing in regions implicated in the processing of emotions were examined as potential mediating factors between difficulties in emotion regulation (DER) and engagement in SMAs. Finally, a moderated mediation model tested the effects of depressive symptoms in such relationships.
      Result: The emotional components associated with SMAs in reward/loss processing included activations in the left anterior insula (AI) and right dorsolateral prefrontal cortex (DLPFC) during anticipation of working to avoid losses. Activations in both the AI and DLPFC mediated the relationship between DER and SMAs. Moreover, depressive symptoms moderated the relationship between AI activation in response to loss anticipation and SMAs.
      Conclusion: The current findings suggest that DER link to SMAs through loss-related brain activations implicated in the processing of emotions and motivational avoidance, particularly in youth with greater levels of depressive symptoms. The findings suggest the importance of enhancing emotion-regulation tendencies/abilities in youth and, in particular, their regulatory responses to negative emotional situations in order to guide moderate engagement in SMAs.
      Competing Interests: Declaration of Competing Interest The authors declared that there were no competing interests exist. Marc N. Potenza has consulted for and advised Opiant Pharmaceuticals, Idorsia Pharmaceuticals, Baria-Tek, AXA, Game Day Data and the Addiction Policy Forum; has been involved in a patent application with Yale University and Novartis; has received research support from the Mohegan Sun Casino and Connecticut Council on Problem Gambling; has participated in surveys, mailings or telephone consultations related to drug addiction, impulse control disorders or other health topics; and has consulted for law offices and gambling entities on issues related to impulse control or addictive disorders. The other authors report no disclosures. Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
      (Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.)
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    • Grant Information:
      UL1 TR001863 United States TR NCATS NIH HHS
    • Contributed Indexing:
      Keywords: Addictive behaviors; Adolescents; Emotion regulation; Insula; Monetary incentive delay; Screen media activities
    • الموضوع:
      Date Created: 20221214 Date Completed: 20221220 Latest Revision: 20230325
    • الموضوع:
      20240105
    • الرقم المعرف:
      PMC9764194
    • الرقم المعرف:
      10.1016/j.dcn.2022.101186
    • الرقم المعرف:
      36516611