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Effect of antenatal and infant micronutrient supplementation on middle childhood and early adolescent development outcomes in Tanzania.

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  • معلومة اضافية
    • المصدر:
      Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8804070 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5640 (Electronic) Linking ISSN: 09543007 NLM ISO Abbreviation: Eur J Clin Nutr Subsets: MEDLINE
    • بيانات النشر:
      Publication: <2003->: London : Nature Publishing Group
      Original Publication: London : J. Libbey, c1988-
    • الموضوع:
    • نبذة مختصرة :
      Background: There is growing evidence that nutritional interventions in the first 1000 days of life may influence long-term health and development outcomes. Few studies have examined the effect of maternal and infant micronutrient supplementation on development outcomes in sub-Saharan Africa.
      Methods: We conducted a follow-up study of two randomized trials of antenatal and infant micronutrient supplementation conducted in Dar es Salaam, Tanzania. We assessed the effect of maternal multiple micronutrient (MMN) supplementation in pregnancy on development of children at 11-14 years of age. We also examined the effect of infant zinc and MMN supplementation on development at 6-8 years of age. We used generalized linear models to assess standardized mean differences (SMDs) in general intelligence, executive function, and mental health scores.
      Results: We followed up 446 children whose mothers were enrolled in the maternal MMN supplementation trial and 365 children who were enrolled in the infant zinc and MMN supplementation trial. We found no effect of maternal MMN supplementation on general intelligence (SMD: -0.03; 95% CI: -0.15, 0.09), executive function (SMD: 0.00; 95% CI: -0.11, 0.11), and mental health scores (SMD: 0.06; 95% CI: 10.10, 0.22). We also found no effect of either infant zinc or MMN supplementation on any of the three development domains (p-values > 0.05).
      Conclusions: We found that antenatal MMN supplementation and infant zinc and MMN supplementation did not have a large effect on development outcomes in middle childhood and early adolescence in Tanzania.
    • References:
      Lu C, Black MM, Richter LM. Risk of poor development in young children in low-income and middle-income countries: an estimation and analysis at the global, regional, and country level. Lancet Glob Health. 2016;4:e916–e22. (PMID: 10.1016/S2214-109X(16)30266-2)
      Black MM, Walker SP, Fernald LCH, Andersen CT, DiGirolamo AM, Lu C, et al. Early childhood development coming of age: science through the life course. Lancet. 2017;389:77–90. (PMID: 10.1016/S0140-6736(16)31389-7)
      Fink G, Peet E, Danaei G, Andrews K, McCoy DC, Sudfeld CR, et al. Schooling and wage income losses due to early-childhood growth faltering in developing countries: national, regional, and global estimates. Am J Clin Nutr. 2016;104:104–12. (PMID: 10.3945/ajcn.115.123968)
      Peet ED, McCoy DC, Danaei G, Ezzati M, Fawzi W, Jarvelin MR, et al. Early childhood development and schooling attainment: longitudinal evidence from British, Finnish and Philippine birth cohorts. PLoS ONE. 2015;10:e0137219. (PMID: 10.1371/journal.pone.0137219)
      Sudfeld CR, McCoy DC, Danaei G, Fink G, Ezzati M, Andrews KG, et al. Linear growth and child development in low- and middle-income countries: a meta-analysis. Pediatrics. 2015;135:e1266–75. (PMID: 10.1542/peds.2014-3111)
      Veena SR, Gale CR, Krishnaveni GV, Kehoe SH, Srinivasan K, Fall CH. Association between maternal nutritional status in pregnancy and offspring cognitive function during childhood and adolescence; a systematic review. BMC Pregnancy Childbirth. 2016;16:220. (PMID: 10.1186/s12884-016-1011-z)
      Borge TC, Aase H, Brantsaeter AL, Biele G. The importance of maternal diet quality during pregnancy on cognitive and behavioural outcomes in children: a systematic review and meta-analysis. BMJ Open. 2017;7:e016777. (PMID: 10.1136/bmjopen-2017-016777)
      Zhu Z, Cheng Y, Zeng L, Elhoumed M, He G, Li W, et al. Association of antenatal micronutrient supplementation with adolescent intellectual development in rural Western China: 14-year follow-up from a randomized clinical trial. JAMA Pediatr. 2018;172:832–41. (PMID: 10.1001/jamapediatrics.2018.1401)
      Dulal S, Liegeois F, Osrin D, Kuczynski A, Manandhar DS, Shrestha BP, et al. Does antenatal micronutrient supplementation improve children’s cognitive function? Evidence from the follow-up of a double-blind randomised controlled trial in Nepal. Lancet Glob Health. 2018;3:e000527.
      Christian P, Murray-Kolb LE, Khatry SK, Katz J, Schaefer BA, Cole PM, et al. Prenatal micronutrient supplementation and intellectual and motor function in early school-aged children in Nepal. JAMA. 2010;304:2716–23. (PMID: 10.1001/jama.2010.1861)
      Prado EL, Sebayang SK, Apriatni M, Adawiyah SR, Hidayati N, Islamiyah A, et al. Maternal multiple micronutrient supplementation and other biomedical and socioenvironmental influences on children’s cognition at age 9-12 years in Indonesia: follow-up of the SUMMIT randomised trial. Lancet. Glob Health. 2017;5:e217–e28.
      Gogia S, Sachdev HS. Zinc supplementation for mental and motor development in children. Cochrane Database Syst Rev. 2012;12:Cd007991. (PMID: 23235652)
      Fawzi WW, Msamanga GI, Urassa W, Hertzmark E, Petraro P, Willett WC, et al. Vitamins and perinatal outcomes among HIV-negative women in Tanzania. N Engl J Med. 2007;356:1423–31. (PMID: 10.1056/NEJMoa064868)
      McDonald CM, Manji KP, Kisenge R, Aboud S, Spiegelman D, Fawzi WW, et al. Daily zinc but not multivitamin supplementation reduces diarrhea and upper respiratory infections in Tanzanian infants: a andomized, double-blind, placebo-controlled clinical trial. J Nutr. 2015;145:2153–60. (PMID: 10.3945/jn.115.212308)
      Winje BA, Kvestad I, Krishnamachari S, Manji K, Taneja S, Bellinger DC, et al. Does early vitamin B 12 supplementation improve neurodevelopment and cognitive function in childhood and into school age: a study protocol for extended follow-ups from randomised controlled trials in India and Tanzania. BMJ Open. 2018;8:e018962. (PMID: 10.1136/bmjopen-2017-018962)
      Institute of Medicine Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B 6 , folate, vitamin B 12 , pantothenic acid, biotin, and choline. Washington, DC: National Academies Press; 1998.
      Holding P, Anum A, van de Vijver FJR, Vokhiwa M, Bugase N, Hossen T, et al. Can we measure cognitive constructs consistently within and across cultures? Evidence from a test battery in Bangladesh, Ghana, and Tanzania. Appl Neuropsychol Child. 2018;7:1–13. (PMID: 10.1080/21622965.2016.1206823)
      Smith ER, Shankar AH, Wu LS, Aboud S, Adu-Afarwuah S, Ali H, et al. Modifiers of the effect of maternal multiple micronutrient supplementation on stillbirth, birth outcomes, and infant mortality: a meta-analysis of individual patient data from 17 randomised trials in low-income and middle-income countries. Lancet Glob Health. 2017;5:e1090–e100. (PMID: 10.1016/S2214-109X(17)30371-6)
      Black MM. Effects of vitamin B 12 and folate deficiency on brain development in children. Food Nutr Bull. 2008;29(Suppl):S126–31. (PMID: 10.1177/15648265080292S117)
      Thomas S, Thomas T, Bosch RJ, Ramthal A, Bellinger DC, Kurpad AV, et al. Effect of maternal vitamin B 12 supplementation on cognitive outcomes in South Indian children: a randomized controlled clinical trial. Matern Child Health J. 2018 https://doi.org/10.1007/s10995-018-2605-z . [Epub ahead of print]. (PMID: 10.1007/s10995-018-2605-z)
      Romero R, Chaiworapongsa T, Espinoza J. Micronutrients and intrauterine infection, preterm birth and the fetal inflammatory response syndrome. J Nutr. 2003;133:1668S–73S. (PMID: 10.1093/jn/133.5.1668S)
      Shenkin SD, Starr JM, Deary IJ. Birth weight and cognitive ability in childhood: a systematic review. Psychol Bull. 2004;130:989–1013. (PMID: 10.1037/0033-2909.130.6.989)
      Twilhaar ES, Wade RM, de Kieviet JF, van Goudoever JB, van Elburg RM, Oosterlaan J. Cognitive outcomes of children born extremely or very preterm since the 1990s and associated risk factors: a meta-analysis and meta-regression. JAMA Pediatr. 2018;172:361–7. (PMID: 10.1001/jamapediatrics.2017.5323)
      Mayo-Wilson E, Junior JA, Imdad A, Dean S, Chan XH, Chan ES, et al. Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years of age. Cochrane Database Syst Rev 2014: Cd009384.
      Niehaus MD, Moore SR, Patrick PD, Derr LL, Lorntz B, Lima AA, et al. Early childhood diarrhea is associated with diminished cognitive function 4 to 7 years later in children in a northeast Brazilian shantytown. Am J Trop Med Hyg. 2002;66:590–3. (PMID: 10.4269/ajtmh.2002.66.590)
      Walker CLF, Lamberti L, Adair L, Guerrant RL, Lescano AG, Martorell R, et al. Does childhood diarrhea influence cognition beyond the diarrhea-stunting pathway? PLoS ONE. 2012;7:e47908. (PMID: 10.1371/journal.pone.0047908)
      Larson LM, Yousafzai AK. A meta‐analysis of nutrition interventions on mental development of children under‐two in low‐and middle‐income countries. Matern Child Nutr. 2017;13 https://doi.org/10.1111/mcn.12229 . (PMID: 10.1111/mcn.12229)
      Kvestad I, Taneja S, Kumar T, Hysing M, Refsum H, Yajnik CS, et al. Vitamin B 12 and folic acid improve gross motor and problem-solving skills in young North Indian children: a randomized placebo-controlled trial. PLoS ONE. 2015;10:e0129915. (PMID: 10.1371/journal.pone.0129915)
      Hajcak G, MacNamara A, Olvet DM. Event-related potentials, emotion, and emotion regulation: an integrative review. Dev Neuropsychol,. 2010;35:129–55. (PMID: 10.1080/87565640903526504)
      Duncan CC, Barry RJ, Connolly JF, Fischer C, Michie PT, Naatanen R, et al. Event-related potentials in clinical research: guidelines for eliciting, recording, and quantifying mismatch negativity, P300, and N400. Clin Neurophysiol. 2009;120:1883–908. (PMID: 10.1016/j.clinph.2009.07.045)
    • Grant Information:
      37701 International U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); K24DK104676 International U.S. Department of Health & Human Services | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (National Institute of Diabetes & Digestive & Kidney Diseases); R01 HD048969 United States HD NICHD NIH HHS; P30 DK040561 United States DK NIDDK NIH HHS; HD048969-01 International U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); K24 DK104676 United States DK NIDDK NIH HHS
    • الرقم المعرف:
      0 (Micronutrients)
      J41CSQ7QDS (Zinc)
    • الموضوع:
      Date Created: 20190206 Date Completed: 20200904 Latest Revision: 20220420
    • الموضوع:
      20240105
    • الرقم المعرف:
      PMC6679819
    • الرقم المعرف:
      10.1038/s41430-019-0403-3
    • الرقم المعرف:
      30718805