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Nosocomial outbreak in a respiratory ward caused by the SARS-CoV-2 Omicron BA 5.2.1 sub-variant associated with non-severe illness in vaccinated patients

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  • معلومة اضافية
    • بيانات النشر:
      Cambridge University Press
    • الموضوع:
      2023
    • Collection:
      Imperial College London: Spiral
    • نبذة مختصرة :
      In this short report, we describe an outbreak of COVID-19 caused by Omicron sub-variant BA.5.2.1 in highly vaccinated patients in a respiratory ward in large acute general hospital in North West London, UK. The attack rate was high (14/33 (42%)) but the clinical impact was relatively non severe including in patients who were at high risk of severe COVID-19. 12/14 patients had COVID-19 vaccinations. There was only one death due to COVID-19 pneumonitis. The findings of this outbreak investigation suggest that while transmissibility of Omicron BA.5.2.1 sub-variant is high, infections caused by this strain are non-severe in vaccinated patients, even if they are at high risk of severe COVID-19 infection.
    • ISSN:
      0950-2688
    • Relation:
      Epidemiology and Infection; http://hdl.handle.net/10044/1/106630
    • الرقم المعرف:
      10.1017/S0950268823001590
    • الدخول الالكتروني :
      https://doi.org/10.1017/S0950268823001590
      http://hdl.handle.net/10044/1/106630
    • Rights:
      © The Author(s), 2023. Published by Cambridge University Press. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http:// creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited. ; https://creativecommons.org/licenses/by/4.0/
    • الرقم المعرف:
      edsbas.8C333866