Parental occupational exposure to benzene and the risk of childhood and adolescent acute lymphoblastic leukaemia:a population-based study

Benzene has been encountered in a variety of occupational settings as an organic solvent and in engine exhaust originating from 1% to 5% levels in gasoline. The International Agency for Research on Cancer has classified benzene as carcinogenic to humans (Group 1) based upon increased risk of acute myeloid leukemia in occupational studies of adults. However, only a small number of studies have reported on the association of parental occupational exposure to benzene and risk of childhood and adolescent leukemias. The associations with acute lymphoblastic leukaemia (ALL) in this population-based study in Denmark. Pediatric cancer cases (